1,16-二?十六?

1,16-二?十六?
英文名	1,16-dibromohexadecane
?名	1,16-二?代十六?
??
CAS?	45223-18-5
SMILES	BrCCCCCCCCCCCCCCCCBr ;
性?
化?式	C 16 H 32 Br 2
摩??量	384.23 g·mol ?1
熔点	53.5?55 °C（326.6?328.1 K） ; 57?58 °C（330?331 K）
	若非注明，所有?据均出自 ?准??（25 ℃，100 kPa）下。

1,16-二?十六? 是一? 有机?化合物，化?式?C ₁₆H ₃₂Br ₂。1,16-二?十六?可由 NBS （或四?化? ^[3]）和1,16-十六?二醇在三?基? 的存在下反?制得。 ^[4]?和 ?化? 在丙? 中回流，可以得到 1,16-二?十六? ； ^[5]?和 ?化? 在二甲基?? 中加?反?，得到1,18-十八?二?。 ^[6]

?考文? [ ?? ]

^ R.G. Woolford. THE ELECTROLYSIS OF ω-BROMOCARBOXYLIC ACIDS . Canadian Journal of Chemistry. 1962-09-01, 40 (9): 1846?1850 [ 2020-11-16 ] . ISSN 0008-4042 . doi:10.1139/v62-280 （英?） .
^ Alexander K.L. Yuen, Falk Heinroth, Antony J. Ward, Anthony F. Masters, Thomas Maschmeyer. Novel bis(methylimidazolium)alkane bolaamphiphiles as templates for supermicroporous and mesoporous silicas . Microporous and Mesoporous Materials. 2012-01, 148 (1): 62?72 [ 2020-11-16 ] . doi:10.1016/j.micromeso.2011.06.036 . （原始?容存? 于2018-06-11）（英?） .
^ Jaejun Lee, Vivian M. Lau, Yi Ren, Christopher M. Evans, Jeffrey S. Moore, Nancy R. Sottos. Effect of Polymerized Ionic Liquid Structure and Morphology on Shockwave Energy Dissipation . ACS Macro Letters. 2019-04-26: 535?539 [ 2020-11-16 ] . ISSN 2161-1653 . doi:10.1021/acsmacrolett.9b00133 . （原始?容存? 于2019-06-07）（英?） .
^ Blanka E. Janicek, Joshua G. Hinman, Jordan J. Hinman, Sang hyun Bae, Meng Wu, Jacob Turner, Huei-Huei Chang, Eugene Park, Rachel Lawless, Kenneth S. Suslick, Catherine J. Murphy, Pinshane Y. Huang. Quantitative Imaging of Organic Ligand Density on Anisotropic Inorganic Nanocrystals . Nano Letters. 2019-09-11, 19 (9): 6308?6314 [ 2020-11-16 ] . ISSN 1530-6984 . doi:10.1021/acs.nanolett.9b02434 . （原始?容存? 于2020-10-06）（英?） .
^ Javier Castilla, Rocio Risquez, Katsumi Higaki, Eiji Nanba, Kousaku Ohno, Yoshiyuki Suzuki, Yolanda Diaz, Carmen Ortiz Mellet, Jose M. Garcia Fernandez, Sergio Castillon. Conformationally-locked N-glycosides: Exploiting long-range non-glycone interactions in the design of pharmacological chaperones for Gaucher disease . European Journal of Medicinal Chemistry. 2015-01, 90 : 258?266 [ 2020-11-16 ] . doi:10.1016/j.ejmech.2014.11.002 . （原始?容存? 于2020-09-23）（英?） .
^ Michele Calas, Mahama Ouattara, Gilles Piquet, Zyta Ziora, Y. Bordat, Marie L. Ancelin, Roger Escale, Henri Vial. Potent Antimalarial Activity of 2-Aminopyridinium Salts, Amidines, and Guanidines . Journal of Medicinal Chemistry. 2007-12, 50 (25): 6307?6315 [ 2020-11-16 ] . ISSN 0022-2623 . doi:10.1021/jm0704752 （英?） .

[1] R.G. Woolford. THE ELECTROLYSIS OF ω-BROMOCARBOXYLIC ACIDS . Canadian Journal of Chemistry. 1962-09-01, 40 (9): 1846?1850 [ 2020-11-16 ] . ISSN 0008-4042 . doi:10.1139/v62-280 （英?） .

[2] Alexander K.L. Yuen, Falk Heinroth, Antony J. Ward, Anthony F. Masters, Thomas Maschmeyer. Novel bis(methylimidazolium)alkane bolaamphiphiles as templates for supermicroporous and mesoporous silicas . Microporous and Mesoporous Materials. 2012-01, 148 (1): 62?72 [ 2020-11-16 ] . doi:10.1016/j.micromeso.2011.06.036 . （原始?容存? 于2018-06-11）（英?） .

[3] Jaejun Lee, Vivian M. Lau, Yi Ren, Christopher M. Evans, Jeffrey S. Moore, Nancy R. Sottos. Effect of Polymerized Ionic Liquid Structure and Morphology on Shockwave Energy Dissipation . ACS Macro Letters. 2019-04-26: 535?539 [ 2020-11-16 ] . ISSN 2161-1653 . doi:10.1021/acsmacrolett.9b00133 . （原始?容存? 于2019-06-07）（英?） .

[4] Blanka E. Janicek, Joshua G. Hinman, Jordan J. Hinman, Sang hyun Bae, Meng Wu, Jacob Turner, Huei-Huei Chang, Eugene Park, Rachel Lawless, Kenneth S. Suslick, Catherine J. Murphy, Pinshane Y. Huang. Quantitative Imaging of Organic Ligand Density on Anisotropic Inorganic Nanocrystals . Nano Letters. 2019-09-11, 19 (9): 6308?6314 [ 2020-11-16 ] . ISSN 1530-6984 . doi:10.1021/acs.nanolett.9b02434 . （原始?容存? 于2020-10-06）（英?） .

[5] Javier Castilla, Rocio Risquez, Katsumi Higaki, Eiji Nanba, Kousaku Ohno, Yoshiyuki Suzuki, Yolanda Diaz, Carmen Ortiz Mellet, Jose M. Garcia Fernandez, Sergio Castillon. Conformationally-locked N-glycosides: Exploiting long-range non-glycone interactions in the design of pharmacological chaperones for Gaucher disease . European Journal of Medicinal Chemistry. 2015-01, 90 : 258?266 [ 2020-11-16 ] . doi:10.1016/j.ejmech.2014.11.002 . （原始?容存? 于2020-09-23）（英?） .

[6] Michele Calas, Mahama Ouattara, Gilles Piquet, Zyta Ziora, Y. Bordat, Marie L. Ancelin, Roger Escale, Henri Vial. Potent Antimalarial Activity of 2-Aminopyridinium Salts, Amidines, and Guanidines . Journal of Medicinal Chemistry. 2007-12, 50 (25): 6307?6315 [ 2020-11-16 ] . ISSN 0022-2623 . doi:10.1021/jm0704752 （英?） .

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