Paul Nurse

Paul Nurse
Paul Nurse
Narozeni	25. ledna 1949 (75 let) ; Norwich nebo Londyn
Alma mater	Birminghamska univerzita ; Vychodoanglicka univerzita ; Harrow High School
Pracovi?t?	Rockefellerova univerzita (2003?2011) ; Kralovska spole?nost (2010?2015) ; Edinburska univerzita ; Francis Crick Institute ; Oxfordska univerzita
Obor	genetika
Ocen?ni	Cena Marjory Stephensonove (1990) ; Novartis Medal and Prize (1991) ; Feldberg Foundation (1991) ; Louis-Jeantet Prize for Medicine (1992) ; Mezinarodni cena Gairdnerovy nadace (1992) ; … vice na Wikidatech
	N?ktera data mohou pochazet z datove polo?ky .

Paul Maxime Nurse ( 25. leden 1949 , Norwich ) je anglicky genetik . V letech 2010-2015 byl prezidentem Kralovske spole?nosti ^[1], v sou?asnosti je ?editelem Ustavu Francise Cricka ^[2] a prezidentem Rockefellerovy univerzity v New Yorku. ^[3] Roku 2001 obdr?el Nobelovu cenu za fyziologii nebo leka?stvi (spolu s Lelandem Hartwellem a Timem Huntem ), a to za objevy v oblasti bun??neho cyklu . ^[4]

?ivot a dilo [ editovat | editovat zdroj ]

Absolvoval na Birminghamske univerzit?, doktorske studium ukon?il v roce 1973 na University of East Anglia , a to v oborech bun??na biologie a biochemie . Roku 1988 se stal vedoucim katedry mikrobiologie na Oxfordske univerzit? . Od roku 2002 vede Britske vyzkumne centrum rakoviny.

Ust?ednim p?edm?tem jeho zajmu je bun??ny cyklus a bun??ne d?leni u kvasinek , zejmena u druhu schizosaccharomyces pombe . Nurse v nich jako prvni objevil gen cdc2 a zarove? ur?il, ?e je to prav? tento gen, ktery hraje kli?ovou ulohu v regulaci bun??neho cyklu, tedy v na?asovani udalosti jako je d?leni bun?k ?i jejich jader. Nurse?v tym p?itom identifikoval stejny gen i u ?lov?ka, ?im? mj. dokazal, ?e zakony bun??neho cyklu jsou stejne u rostlin, zvi?at i ?lov?ka. P?edev?im za tento objev obdr?el Nobelovu cenu. Objev m??e mit i zasadni dopad na leka?stvi, zejmena le?bu rakoviny , nebo? rakovinne bu?ky maji bun??ny cyklus naru?eny, co? umo??uje jejich masivni d?leni ? le?ba by mohla spo?ivat v obnov? klasickeho cyklu. ^[5]

Odkazy [ editovat | editovat zdroj ]

Reference [ editovat | editovat zdroj ]

Externi odkazy [ editovat | editovat zdroj ]

Obrazky, zvuky ?i videa k tematu Paul Nurse na Wikimedia Commons
Host: Paul Nurse, nositel Nobelovy ceny za fyziologii. Moderuje: Daniel Stach na ?T24

[1] ttps://royalsociety.org/people/paul-nurse-12012/

[2] ttp://www.crick.ac.uk/research/a-z-researchers/researchers-k-o/paul-nurse/

[3] ttp://www.rockefeller.edu/research/faculty/labheads/PaulNurse/

[4] ttp://www.nobelprize.org/nobel_prizes/medicine/laureates/2001/nurse-bio.html

[5] ttps://www.jcu.cz/o-univerzite/media-a-propagace/tiskove-zpravy/tiskove-zpravy-2015/8-4-2015-jihoceskou-univerzitu-navstivi-drzitel-nobelovy-ceny-sir-paul-nurse-1

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Nositele Nobelovy ceny za fyziologii a leka?stvi

1901?1925	Emil von Behring (1901) Ronald Ross (1902) Niels Ryberg Finsen (1903) Ivan Petrovi? Pavlov (1904) Robert Koch (1905) Camillo Golgi / Santiago Ramon y Cajal (1906) Alphonse Laveran (1907) Ilja Ilji? Me?nikov / Paul Ehrlich (1908) Emil Theodor Kocher (1909) Albrecht Kossel (1910) Allvar Gullstrand (1911) Alexis Carrel (1912) Charles Richet (1913) Robert Barany (1914) Jules Bordet (1919) August Krogh (1920) Archibald Hill / Otto Fritz Meyerhof (1922) Frederick Banting / John James Rickard Macleod (1923) Willem Einthoven (1924)

1926?1950	Johannes Fibiger (1926) Julius Wagner-Jauregg (1927) Charles Nicolle (1928) Christiaan Eijkman / Frederick Hopkins (1929) Karl Landsteiner (1930) Otto Heinrich Warburg (1931) Charles Scott Sherrington / Edgar Douglas Adrian (1932) Thomas Morgan (1933) George Whipple / George Richards Minot / William Parry Murphy (1934) Hans Spemann (1935) Henry Hallett Dale / Otto Loewi (1936) Albert Szent-Gyorgyi (1937) Corneille Heymans (1938) Gerhard Domagk (1939) Henrik Dam / Edward Adelbert Doisy (1943) Joseph Erlanger / Herbert Spencer Gasser (1944) Alexander Fleming / Ernst Boris Chain / Howard Walter Florey (1945) Hermann Joseph Muller (1946) Carl Ferdinand Cori / Gerty Coriova / Bernardo Houssay (1947) Paul Hermann Muller (1948) Walter Rudolf Hess / Antonio Egas Moniz (1949) Philip Showalter Hench / Edward Calvin Kendall / Tadeus Reichstein (1950)

1951?1975	Max Theiler (1951) Selman Abraham Waksman (1952) Hans Adolf Krebs / Fritz Albert Lipmann (1953) John Franklin Enders / Frederick Chapman Robbins / Thomas Huckle Weller (1954) Hugo Theorell (1955) Andre Frederic Cournand / Werner Forßmann / Dickinson W. Richards (1956) Daniel Bovet (1957) George Wells Beadle / Edward Lawrie Tatum / Joshua Lederberg (1958) Arthur Kornberg / Severo Ochoa (1959) Frank Macfarlane Burnet / Peter Brian Medawar (1960) Georg von Bekesy (1961) Francis Crick / James Dewey Watson / Maurice Wilkins (1962) John Carew Eccles / Alan Lloyd Hodgkin / Andrew Fielding Huxley (1963) Konrad Bloch / Feodor Lynen (1964) Francois Jacob / Andre Lwoff / Jacques Monod (1965) Francis Peyton Rous / Charles Brenton Huggins (1966) Ragnar Granit / Haldan Keffer Hartline / George Wald (1967) Robert W. Holley / Har Gobind Khorana / Marshall Warren Nirenberg (1968) Max Delbruck / Alfred Hershey / Salvador Luria (1969) Julius Axelrod / Ulf von Euler / Bernard Katz (1970) Earl Wilbur Sutherland (1971) Gerald Edelman / Rodney Robert Porter (1972) Karl von Frisch / Konrad Lorenz / Nikolaas Tinbergen (1973) Albert Claude / Christian de Duve / George Emil Palade (1974) David Baltimore / Renato Dulbecco / Howard Martin Temin (1975)

1976?2000	Baruch Samuel Blumberg / Daniel Carleton Gajdusek (1976) Roger Guillemin / Andrew Schally / Rosalyn Yalowova (1977) Werner Arber / Daniel Nathans / Hamilton O. Smith (1978) Allan McLeod Cormack / Godfrey N. Hounsfield (1979) Baruj Benacerraf / Jean Dausset / George Davis Snell (1980) Roger W. Sperry / David H. Hubel / Torsten Wiesel (1981) Sune Bergstrom / Bengt Samuelsson / John Vane (1982) Barbara McClintockova (1983) Niels Kaj Jerne / Georges Kohler / Cesar Milstein (1984) Michael S. Brown / Joseph L. Goldstein (1985) Stanley Cohen / Rita Leviova-Montalciniova (1986) Susumu Tonegawa (1987) James W. Black / Gertrude Belle Elionova / George H. Hitchings (1988) J. Michael Bishop / Harold E. Varmus (1989) Joseph Murray / E. Donnall Thomas (1990) Erwin Neher / Bert Sakmann (1991) Edmond H. Fischer / Edwin G. Krebs (1992) Richard John Roberts / Phillip A. Sharp (1993) Alfred G. Gilman / Martin Rodbell (1994) Edward B. Lewis / Christiane Nussleinova-Volhardova / Eric F. Wieschaus (1995) Peter C. Doherty / Rolf Martin Zinkernagel (1996) Stanley B. Prusiner (1997) Robert F. Furchgott / Louis Ignarro / Ferid Murad (1998) Gunter Blobel (1999) Arvid Carlsson / Paul Greengard / Eric Kandel (2000)

2001?	Leland H. Hartwell / Tim Hunt / Paul Nurse (2001) Sydney Brenner / H. Robert Horvitz / John Sulston (2002) Paul Lauterbur / Peter Mansfield (2003) Richard Axel / Linda B. Buckova (2004) Barry Marshall / Robin Warren (2005) Andrew Z. Fire / Craig C. Mello (2006) Mario Capecchi / Martin Evans / Oliver Smithies (2007) Harald zur Hausen / Francoise Barre-Sinoussi / Luc Montagnier (2008) Elizabeth Blackburnova / Carol W. Greiderova / Jack W. Szostak (2009) Robert G. Edwards (2010) Bruce Beutler / Jules A. Hoffmann / Ralph M. Steinman (2011) John Gurdon / ?in’ja Jamanaka (2012) James Rothman / Randy Schekman / Thomas Sudhof (2013) John O'Keefe / May-Britt Moserova / Edvard Moser (2014) William C. Campbell / Sato?i Omura / Tchu Jou-jou (2015) Jo?inori Osumi (2016) Jeffrey C. Hall / Michael Rosbash / Michael W. Young (2017) James P. Allison / Tasuku Hond?o (2018) Gregg L. Semenza / Peter J. Ratcliffe / William Kaelin (2019) Harvey J. Alter / Michael Houghton / Charles M. Rice (2020) David Julius / Ardem Patapoutian (2021) Svante Paabo (2022) Katalin Karikoova / Drew Weissman (2023)