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??? ?? ??????????? ???????????????? ???? ????? ??????? ????? ???, ???? ??????? ??????????? ??????????????? ??????? ?????????? ????????????? ??? ????? ?????????? ??????? ????, ?? ??? ???? ???????????? ??? ?????? ?????? ???? ???? ???
??????? ??????? ??????????? ????????????????? "??????????" ???? ???? ???? ?????? ???????? ????????; ????? ?????????? ?????????? ??? ???????? ???????????????? ??????????
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?? ??????????? ??? ???????? ????????????? ???????? ???? ???? ???????? ?? ?????? ??????????? ??????? ?????? ?????????????? ????? ?????????? ??????????? ??????????? ??? ??? ??????? ??????????? ??????????? ???????????, ?? ????? ???? ??
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??????????
), ??? ???????? ??????????? ???????? ????? ???? ???????? ??????, ???
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???? ????, ???????, ????? ???????????????? ????????? ???????? ????, ?????????? ????????? ??????, ?? ???????? ?????? ???????????????? ????????? ??????? ??? ??????? ????
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??????? ??????? ????? ????????? ???????????? ??????? ???? ???? ??????? ????????? ????????, ?? ???????? ???? ?????? ?????????
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???????? ??? ??????
[
????????
]
???????? ????? ????? ????????? ????, ????? ???????, ???????? ????
???????
???? ???? ????? ???????? ???? (??????)
????????? ?????????,
[??]
??????? ????????????? ??? ?????????? ??????????? ???????????????? ?????? ????? ???? ??? "????????? ? ????????? ?????? ???? ??????? ????" ???? ???? ??????? ??????? ??????
??????? ????
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[??]
???? ???? ?????
???? ????????
?????? ????????
???? ????, ??????? ????? (????? ???????? ??????) ????
??? ?????? ??????????? ????????
??? ???? ???? ????????? ?????? ??????????
???????? ?? ???? ????????
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??????-???????????? ??????? ????? ?????? ?????,
[??]
???????????,
????? ???????????? ????????????
??-???????, ??? ??????????
??????? ??????? ????????
?????? ????????? ???? ??????? ???? ??????-
??????? ??????? ?????????
??-???????? ?????, ??? ??? ????? ???????????? ???????????? ???? ????? ????
??????? ? ??????? ?????????
???? ???????? ??????? ??????
[??]
??????? ???? ????
?????? ?? ??? ??????? ?????????
(?????) ??? ???? ????
???? ????????
??????? ??? ???? ???? ??? ???? ???? ??? ???????
?????????????? ???????? ?????? ?????????
???????? ???? ???????
[??]
[??]
???? ???? ????
??????? ??????? ???
???????????
[??]
???????????? ????????? ????, ???? ???? ?????????
???? ?????
???
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????
??????? ????? ????????
?????? ??? ????????
[??]
???? ???? ????
?????
??????? ????? ????????
???????? ??????????
[??]
- ↑
?
?
"GSK snaps up Domantis to move into biotech field"
?
The Independent
? ? ???????? ?????
- ↑
?
?
The
Scientific Founders
????????? ??????
??????????
?? ?????????? ???? ?????? of Bicycle Therapeutics Ltd. ? Christian Heinis and Sir Greg Winter, FRS.
- ↑
"EMBO MEMBER: Gregory P. Winter"
?
people.embo.org
?
- ↑
"Doctor Gregory P. WINTER | Jeantet"
? ? ??????? ?????
- ↑
"Announcement of the Prince Mahidol Award 2016"
? princemahidolaward.org? ?? ??????? ???? ??????
???
???? ??????? ???
? ???????? ????? ?? ??? ????
?
- ↑
?
?
?
"WINTER, Sir Gregory (Paul)"
?
??'? ??
?
ukwhoswho.com
?
2016
(online
Oxford University Press
???????)? ? ??????? ?? ???????, ???????????? ???????? ?????? ????????
(???????????? ??
???? ?????? ????????? ???????
????????)
(??????? ???????????)
- ↑
"Sir Gregory P. Winter ? Facts ? 2018"
?
NobelPrize.org
? Nobel Media AB? ? ??????? ????
? ???????? ????? ? ??????? ????
?
- ↑
McCafferty, J.
; Griffiths, A.;
Winter, G.
;
Chiswell, D.
(????)? "Phage antibodies: filamentous phage displaying antibody variable domains"?
Nature
?
348
(6301): 552?554?
??????????
4258014
?
?????
:
10.1038/348552a0
?
????????
2247164
?
??????
:
1990Natur.348..552M
?
- ↑
"Trinity College Cambridge"
? ? ????? ???? ??????
???
???? ??????? ????
- ↑
????????:Scopus
- ↑
Winter, G; Griffiths, A. D.; Hawkins, R. E.; Hoogenboom, H. R. (????)? "Making antibodies by phage display technology"?
Annual Review of Immunology
?
12
: 433?455?
?????
:
10.1146/annurev.iy.12.040194.002245
?
????????
8011287
?
- ↑
Griffiths, A. D.; Williams, S. C.; Hartley, O; Tomlinson, I. M.; Waterhouse, P; Crosby, W. L.; Kontermann, R. E.; Jones, P. T.; Low, N. M.; Allison, T. J. (????)?
"Isolation of high affinity human antibodies directly from large synthetic repertoires"
?
The EMBO Journal
?
13
(14): 3245?60?
?????
:
10.1002/j.1460-2075.1994.tb06626.x
?
????????
8045255
?
??????
395221
?
- ↑
Hoogenboom, H. R.; Griffiths, A. D.; Johnson, K. S.; Chiswell, D. J.; Hudson, P.; Winter, G. (????)?
"Multi-subunit proteins on the surface of filamentous phage: Methodologies for displaying antibody (Fab) heavy and light chains"
?
Nucleic Acids Research
?
19
(15): 4133?4137?
?????
:
10.1093/nar/19.15.4133
?
????????
1908075
?
??????
328552
?
- ↑
Anon (????)?
"The inventor of humanized monoclonal antibodies and cofounder of Cambridge Antibody Technology, Greg Winter, muses on the future of antibody therapeutics and UK life science innovation"
?
Nature Biotechnology
?
29
(3): 190?
??????????
205275386
?
?????
:
10.1038/nbt.1815
?
????????
21390009
?
- ↑
Winter, G.
;
Fields, S.
;
Brownlee, G. G.
(????)? "Nucleotide sequence of the haemagglutinin gene of a human influenza virus H1 subtype"?
Nature
?
292
(5818): 72?5?
??????????
4312205
?
?????
:
10.1038/292072a0
?
????????
7278968
?
??????
:
1981Natur.292...72W
?
- ↑
Fields, S.
;
Winter, G.
;
Brownlee, G. G.
(????)? "Structure of the neuraminidase gene in human influenza virus A/PR/8/34"?
Nature
?
290
(5803): 213?7?
??????????
8051512
?
?????
:
10.1038/290213a0
?
????????
7010182
?
??????
:
1981Natur.290..213F
?
- ↑
Riechmann, L.; Clark, M.; Waldmann, H.; Winter, G. (????)? "Reshaping human antibodies for therapy"?
Nature
?
332
(6162): 323?7?
??????????
4335569
?
?????
:
10.1038/332323a0
?
????????
3127726
?
??????
:
1988Natur.332..323R
?
- ↑
Marks, J. D.; Hoogenboom, H. R.; Bonnert, T. P.; McCafferty, J.; Griffiths, A. D.; Winter, G. (????)? "By-passing immunization"?
Journal of Molecular Biology
?
222
(3): 581?97?
?????
:
10.1016/0022-2836(91)90498-U
?
????????
1748994
?
- ↑
?
?
"Live blog: direction evolution takes chemistry Nobel prize"
? ???????? ????? ? ??????? ????
?
- ↑
"Nobel Prize in Chemistry 2018 ? live"
?
The Guardian
? ? ??????? ????
? ???????? ????? ? ??????? ????
?
- ↑
http://www.takedasf.com/corporate/winter.htm
?
[
??????????? ???????? ?????
]
- ↑
"Sir Gregory Winter Chairman"
? ?? ????????? ???? ??????
???
???? ??????? ????
- ↑
"Greg Winter wins 2018 Nobel Prize for Chemistry - MRC Laboratory of Molecular Biology"
?
MRC Laboratory of Molecular Biology
? ? ??????? ????
? ???????? ????? ? ??????? ????
?
- ↑
Winter, Gregory Paul (????)?
The amino acid sequence of tryptophanyl RNA synthetase from bacillus stearothermophilus
(??????????)? University of Cambridge?
???????
500591023
?
????????:EThOS
?
- ↑
Winter, G. P.; Hartley, B. S. (????)? "The amino acid sequence of tryptophanyl tRNA Synthetase fromBacillus stearothermophilus"?
FEBS Letters
?
80
(2): 340?342?
????????
0014-5793
?
??????????
39202845
?
?????
:
10.1016/0014-5793(77)80471-7
?
????????
891985
?
- ↑
"King Faisal Prize | Professor Sir Gregory P. Winter"
?
kingfaisalprize.org
(?????? ??????)
? ???????? ????? ????-??-??
?
- ↑
"Scientific Advisory Board"
? Heptares
? ???????? ????? ? ?????? ????
?
- ↑
???? ??????
?????? ????????
??????? ?????????
????????????
- ↑
"The Nobel Prize in Physiology or Medicine 1984"
?
NobelPrize.org
? ???????? ????? ? ??????? ????
?
- ↑
"Therapeutic Antibodies - MRC Laboratory of Molecular Biology"
?
MRC Laboratory of Molecular Biology
? ???????? ????? ? ??????? ????
?
- ↑
"Greg Winter"
?
MRC Laboratory of Molecular Biology
?
- ↑
"Sir Gregory Winter | Royal Society"
?
- ↑
Gregory Winter (? ?? ????)?
"Gregory Winter: Executive Profile & Biography ? Businessweek"
?
Bloomberg BusinessWeek
? ???????? ????? ? ?????? ????
?
- ↑
"www.bicycletherapeutics.com"
? bicycletherapeutics.com? ?? ???????? ????
? ???????? ????? ? ?????? ????
?
- ↑
"Covagen AG | September 2011: Sir Gregory Winter joins Covagen's Scientific Advisory Board"
? Covagen.com? ?? ?????????? ????? ?? ?????? ???? ??????
???
???? ??????? ???
? ???????? ????? ? ?????? ????
?
- ↑
"Covagen AG | Scientific Advisory Board"
? Covagen.com? ?? ?????? ???? ??????
???
???? ??????? ???
? ???????? ????? ? ?????? ????
?
- ↑
Lawrence, Stacy (????)?
"Billion dollar babies?biotech drugs as blockbusters"
?
Nature Biotechnology
?
25
(4): 380?2?
??????????
205266758
?
?????
:
10.1038/nbt0407-380
?
????????
17420735
?
- ↑
"Global Pharmaceutical 2017 Industry Statistics"
(??????)
? ? ??????? ???? ??????
???
(??????)
???? ??????? ???
? ???????? ????? ? ??????? ????
?
- ↑
http://www.astrazeneca.com/media/latest-press-releases/2006/5266?itemId=3891617
????????? ??????
??????????
? ????????? ???? ??????
- ↑
GSK is to buy Domantis ? a company based on discoveries by MRC scientists
????????? ??????
??????????
?? ????????? ???? ?????? LMB webpage
- ↑
Heinis, C.; Rutherford, T.; Freund, S.; Winter, G. (????)? "Phage-encoded combinatorial chemical libraries based on bicyclic peptides"?
Nature Chemical Biology
?
5
(7): 502?507?
?????
:
10.1038/nchembio.184
?
????????
19483697
?
- ↑
"Sir Gregory Winter CBE FMedSci FRS"
? London:
Royal Society
? ?? ??????? ???? ??????
???
???? ??????? ????
- ↑
"Royal Society announces 2011 Copley Medal recipient"
? Royal Society? ? ????? ???? ??????
???
???? ??????? ???
? ???????? ????? ?? ??????????? ????
?
- ↑
"LMB Structure"
? ?? ??????????? ???? ??????
???
???? ??????? ????
- ↑
"Advisory Council of the Campaign for Science and Engineering"
? ?? ????? ???? ??????
???
???? ??????? ???
? ???????? ????? ?? ??????????? ????
?
- ↑
"Sir Gregory Winter CBE FRS appointed Master of Trinity College, Cambridge University"
? 10 Downing Street? ?? ???????? ????
? ???????? ????? ? ?????? ????
?
- ↑
"Master of Trinity College, Cambridge &' events"
? University of Cambridge? ?? ????? ???? ??????
???
???? ??????? ???
? ???????? ????? ? ?????? ????
?
- ↑
Sir Gregory Winter
, retrieved on 17 March 2020 in Wilhelmexner.org
- ↑
Franklin-Wallis, Oliver (?? ?? ????)?
"From pandemics to cancer: the science power list"
?
The Times
(?????? ??????)?
????????
0140-0460
? ???????? ????? ????-??-??
?
????????:CC-notice
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