????? ?????
(
?????????????
,
Poliomyelitis
) ?? ??????
?????
???
????
??
????? ??????
, ?????? ?? ???
???? ??????
. ????? ?????? ???? ????, ????? ???????
????? ????-??
. ?????????? ?? ????? ?? ??????? ??? ?-90% ??????? ??, ???? ?? ????? ???? ?
????? ???
?????? ?????? ????? ?????? ??? ?? ?????????. ?????? ??? ??????????? ???? ????? ?
????? ?????? ???????
, ???? ????????? ????????, ????? ?
?????
??????? ??? ?? ????? ?? ???? ?????? ???????. ????? ????? ?? ????? ?????? ?????? ??? ????? ?????? ???????. ????? ????? ?
??? ?????
??? ????? ??????, ???????? ?????? ?-??????? ?????? ???? ?? ???????. ?????? ??????, ??? ?????? ?
?????
?
?????
?
?????
???? ??????, ????? ????? ????? ?? ?
????
.
??????? ???? ??? ??????? ?? ????? ????? ????? ???????, ????? ?
??????
????????
??? ??????
, ?? ?? ???? ???????
????? ?????
, ??? ?? ?
????
,
??????
??????
?
?????
.
???? ??? ????? ?????? ??????? ??????? ?????, ????? ????? ?? ???? ?? ?????? ?????? ???? ??????
???? ??????? ?? ???? ??????
. ???? ?????? 2019 ?????? ???? 2 ?-3 ?? ?????? ????? ????? ????? ???? ??? 1.
[1]
?????????? ?????? ?????? ??????? ???? ?????? ??????? ??? ?
??? ?????????
. ??????? ?????? ??? ??????
????? ??????
?????? ????? ???? ????? ??????, ?????? ??????? ?
?????
???? ????. ?????? ????? ?? ????? ???
???? ?????
(
??'
)
?-
1840
??????
???? ????? ????
(
??'
)
?-1890 ???? ???? ???? ????? ?????
???? ?????-????
. ?????? ????? ?? ????? ???
??? ?????????
?-
1908
.
[2]
?? ?? ?? ????? ??? ???? ?-19 ?? ??? ??????
??????
?????? ?? ?????, ????? ???? ?-20 ??? ?????? ??? ?????? ?????? ????? ?????. ?????? ????? ????? ??? ?????? ?????, ????? ?????? ??????; ????? ???? ?????? ?????? ????? ??? ????????? ???????.
???? ?????? ?????? ???? ???? ???? ?
?????
?????
?? 1880, ???? ??????? ??????? ?????? ??????; ??? ??? ???? ??? ?????? ?????? ?? ?????? ?????. ?-1910 ??? ???? ?????? ???? ????? ???? ????? ???? ?????? ??????? ????? ??? ?????? ????, ????? ????? ????? ????? ????. ?????? ??? - ??????? ????? ????? ???????? ??????? - ????? ?????? ?????? ?????? ????? ?????. ????? ???? ??????? ???? ????? ?????, ??????? ???? ????? ?? ???? ?????? ????? ????? ??? ??? ?????? ??????? ???.
[3]
????? ????? ??????
????? ??????? ??????
,
?????"?
??????
?????
?????? ????? ?
????? ?????? ?? ?????
.
?????
??
- ??? ??? ??? ???????? ???? ??1% ?????? ???? ????? ??? ???? ???? ??????? ???????? ????? ?????. ?????? ??? ???? ???? ???????. ??? ????? ????? ?????? ????? ????? ???? ??? ????. ??? ?????? ???? ??? ?????? ??????? ???? ???? ????? ?????? ???????, ?? ???? ?????? ?????? ???? ?????? ?????? ?? ????? ???? ?? ???.
????? ?
???? ????????
- ??????? ????? ??????? ?????? ???????.
????? ?????? ?????? - ??????? ????? ????? ?????? ????????.
???? ???? ????
- ??? ????? ???? ???? .
??25% ??????? ?????? ?????? ????? ?? ????? ????? post-polio syndrome ??????? PPS. ?????? ??? ???? ?????? ????? ???? ???? ????? ????????. ????? ??????? ?? ???? ???? ???? ?????? ????? ??? ?????? ??????, ?????? ????? ?????? ?????? ??? ????? ????? ???? ?????? ??????? ????? ??????.
???? ????? ??????? Post Polio Syndrome
[
????? ??? ????
|
?????
]
????? ????? ??? ???? ????? ??????? ?????? ????? ????? ????? ?????. ????? ?? ????? ?? ?? ????? ??????, ??? ??????? ?????? ?????? ????? ??????? ?????? ??? ?????? ????? ????? ?????? ??????? ?????? ???? ?????. ?? ???? ?? ????? ??????, ??? ?? ????? ?? ??????? ?????? ?
??????????
.
[4]
[5]
- ??? ????? ?
????? ??? ???? ????? ?????
???? ???? ????? ?? ????, ?
???? ???????
?? ???? ?-20 ??? ?????? ???????? ?????
???????
??? ?????, ??? ???? ???? ???? ?? ????? ?????? ????? ?????? ?????? ?? ???? ???? ????? ??????? ????? ?-350,000 ????
1988
?-74 ???? ????
2015
.
[6]
?? ?????? ?????? ???? ?"?
???? ????
??????? ???? ???? ????? ?????? (IPV). ???? 1954, ???? ??????? ???? ???? ?? ?????, ?????? ????????, ???? ????? ????? ??????? ????? ???? ?-500,000 ??????? ????? ????? ?????.
[7]
???? ???, ????
1962
???? ?????? ????? ????? ?????? ?????? ???? ????? ?? ??? ?"?
????? ??????
?????? ?? ???? ????? ????? ?????? ??? ??? (OPV). ????? ???? ????? ????? ?????? ??? ??? ???????? ?????? ???, ????? ?????????? ?????????????? ????? ??-Baylor College of Medicine ?
??????
????? ?????
??? ???? ?????? ??????.
[8]
[9]
[10]
[11]
????? ?????? ?????? ?????? ???? ??????? ?????? ?? ?? ?????? ??????, ???? ???? ???? ??????. ????? ????? ????? ?????? ??????? ????? ?????? ?? ??? ????? ?????. ?????? ?????? ?????? ??? ???? ??? ????? ????? ?? ?????????? ??? ????? ??????, ???? ????????? ?????? ?? ?? ??????? (????? ????). ?????? ?? ???? ????? ??? ??????? ?????? (??? ?-750,000 ???????) ????? ?????? ???? ????? ????? ????? ????, ??? ?????? ????? ????? ??????? ?????? ???????? ???? ?????? (????? ??? ??????? ????? ????? ?????? ??? ?????). ?????? ????? ????? ????? ???? ???? ??? ????? ???-??????? ?????????? ????. ?? ???, ????? ???? ????? ?? (??? ???), ????? ?????, ???????? ?????? ???? ?????? ??? ?? ???? ???? ?? ??? ??????????, ?????? ??? ???????? ???? ????? ???? ????? ?????? ??, ?????? ?????? ????? ????.
????? ????? ?????? ???? ???? ????? ????? ???? ????? ????? ????, ?? ??????? ?? ???? ????; ?? ??? ??? ???? ???? ????? ???? ?????????? ??? ?????, ???? ?????? ??????, ????? ????? ????????? ??????, ???? ?? ????? ??????? ???????.
??? ???????? ????? ?????? ???? ?????? ???????? ???? ??? ???? ????. ??? ??? ??????? ?????? ?????? IPV ???? ?????? (?? ?? ???? ???? ???????), ???? ?????? ?-OPV ???? ??? ?????.
?????? ????? ??? ????? ???????? ??????? ?? ????? ?-IPV ??????, ?????? ???????? ????? ???? ????? ?? ?-OPV ??????, ?? ?????? ???? ?????? ?? ?????. ?????? ??? ????? ?????? ????? ?????? ?-OPV ???? ????? ????? ????, ????? ???? ??????????? ????? ?-IPV. ?????? ????? ????? ???? ??????? ???? ?????? ?????? ??? IPV. ????? ??? ????? ?????? ????? ???? ????? ?????? ?-OPV.
????? ?? ??????? ??? ????? ????? ???? ????? ??????? ????? ???? ?????? (??? ?? ????? ?????), ????? OPV ???? ???? ??????.
????? ???? ?????? ????? ?
???????????
- ????????,
???????????
, ?? ?????????? ??????? ???????? ?????? ?????? ?????, ?? ???? ?????? ???? ?????? ?????, ????? ????? ?????.
?????? ?????? ???? ?????? ?????? ????? ??? ????? ?? ????? ???? ??????? ??????? ????? ??????. ????? ???, ??? ????? ??????, ??? ???????? ?????? ????? ??????. ????? ?? ???? ?? ??? ??? ?????? ????? (??????) ???? ??? ?????? ??????.
?? ??? ????, ?????? ????? ??????? ?? ????????? ?? ?????? ?-OPV ?????? ?????
???????
????? ???? ??????, ?????
????
?
????
.
[12]
???? ????? ????? ????? ?????? ???? ?????? ??? ??????? ?????.
[13]
?????? ?????? ???? ?????? ????? ????? ???? ??????? ?????? ??????. ???? ?????? ???? ?????? ????? ??????.(enteroviruses) ????? ????? ????? ????? ???? ????? ?????? ????? ?????. ???? ????? ????? ???? ????? ???? ?????? ????, ????? ????????, ???? ????? ??????? ???????? ????? ????? ????? ???? ????.
???? ????? ?????? ?????? ????? ???????
[
????? ??? ????
|
?????
]
?? ????
1949
????? ???? ????? ????? ????? ????? ??????, ?? ????? ?????? ?? ????? ????.
[14]
?????? ???? ?? ??? 1949 ???? ??????? ??? ???? ???? ???? ?? 338 ?????.
[15]
????? ?????? ?????? ?? ????? ?????, ??? ????
1954
??? ?????? 4,700 ????? ???????? ?? ?????, ???? ????? ????? 760 ?????.
[16]
?????, ??? ??? ?? ?? ??? ??? ?????? ?????? ?
????? ????
?
?????
???? ??????? ??????, ???? ?????? ???????? ?????? ????. ?????? ??? ??? ????
1952
???? ?-1,400 ??? ?????? ????.
??? ????? ????? ?????? ??? ??????? ?????? ?????? ???????? ???????? ??????? ???????, ???? ??? ?????? ????? ??????? ??????? ????? ?? ???? ???? ??????, ????? ?????? ?? ??????? ?????? ?????? ?? ??????? ??????? ??? ?????? ???? ?????? ????
[17]
.
???? ????? ???? ?????? ???? ?????? ??????? ????????? ?????. ????? ?-50 ??? ?????? ?-4,700 ??? ??-760 ????? ?????. ???? 1957 ???? ?????? ???? ??? ?????, ???? ??? ???????? ???? ???????, ???? ????? ??? ???? 1989 ?? ???? ?? ???? ????? ??????.
???? ??"?
???? ????
???? ?? ????? ?????? ???? ????? ????? ???? ??? ?????? ???????? ????? ?????? ????? ?-
1955
, ???? ???? ?????? ??????? ?????? ?? ????? ????? ?? ????? ????? ?? ??????. ??? ?? ????? ????? ????? ?????? ????? ????? ??????. ????'
??? ????????
???? ?? ?????? ???? ??? 1955, ?????? ??????
1956
??? ???? ????????. ??? ????
1958
????? ????? ?? 90% ????? ??????? ???? ????? ??????,
[18]
?????? ???? ?????? ??????.
???????? ??????? ?????? ????? ???? 1988, ?? ????? ????? 15 ???.
[19]
?-
1989
, ????? ??????? ??????? ???? ??? ????? ???? ???? ?????? ??? ?????? ???? ?? ???? ?? ???? ????? ??? ????? ??????, ?? ???? ?????? ?????? ????? ?? ?????? ????? ????????. ?
????
2005
????? ?? ????? ???????? ???????? ?????? OPV ???? ??????, ????? ?????? ????? ?????? ???? ?? ?? ????? ?????. ????? ?? ???? ??? ????? ????? ??????? ???????, ????? ??????, ??? ??? ???? ?????? ????? ????? ?' ???? ????.
[20]
????
2013
????? ?????? ????? ?? ???? ?????? ??? ?????? ?? ????? ?????? ???????? ???
???
,
?????
,
????
,
????? ??
,
??????
,
??? ???
????? ??????. ?????? ??? ??? ???? ??????? ??????
??????
2013 ????? ???? 150,000 ????? ?????? ????
2004
????? ???? ??? ???? ??????, ?????? ?????? ????? ?????? ???? ???????. ????? ??? ???? ?????
???? ???????
?? ????? ???? ????? ?????? ???????? ????? ??? ???? ????.
[21]
????
2022
????? ?????? ???? ???? ?? ????? ????? ??????. ???? ??????? ????? ?? ????? ????????????? ???? ?? ????? ???? ????? ??????? ????.
[22]
???? ?? ??? ?????? ?? ???? ????? ?????? ??? 1989 ??????.
???? 2022 ???? ????? ?
?????
??
??????? ?????
????? ???? ?? ????? ?
??? ???
??
???????
.
[23]
??????? 2022 ??? ????? ???? ????? ????? ????????.
[24]
?????? 2023 ?????? ???? ?????? ???? ???? ???? ?????? 3 ????????? ?????? ???? ????? ???? ???? ????.
??? ??? 1988 ????? ?????? ????? ????? ??????? ?? ?????? ?????? ??? ????? ?????, ?????? ????? ?? ??? ????? ??????? ????, ?????? ?????? ??????? ??? ???? ???? ???? ???????
[13]
.
??? ????? ??? ???? ?????? ?????? ?????? ???? ????? ?????? ????, ????? ??? ?????. ?? ???, ?????? ??? ???? ?? ???????? ?????????? ????????? ???? ?? ?????. ?? ????? ?????? ???? ?? ???? ????? ????
[13]
. ???? ??????? ?????? ???? ?????? ?? ?????????? ??????? ????? ????? ?????? (?????? ?? ??? 95%) ???? ???? ??????. ?????? ?????? ???? ?????? ???? ????? ???????? ?????? ??? ???? 1957. ?-1988, ?????? ??????? ?????? ??????? ??????, ?????? ???? ????? ????? ??????? ????? ?? ????? ????? ????? ?? ??? 40.
[13]
????? ????? ??????? ?????? ???? ?????? ???? ???? ?? ????? ??????? ????? ????, ???? ????? ?????? ???? ??? ????? ???? ????? ????????. ??? ?? ????? ???????? ?????? ????? ??? ?????? ??????? ??? ??? ??????? ????? ??? ????? ????? ?? ????? (???? ????, ?????? ??????? ????).
???? ????? ?????? ????????? ?? ??????? ??????? ????? ?????? ???? ??? ???? ?????? ?????.
[25]
????
2007
???? ??????
??? ????? ?????? ?????
, ????"?-2007, ??????, ????? ????? 1 ?? ????: "????? ?? ????? ?????? ???? ?????? ????? ????? ????? ???? ???? ?? ???????? ?? ????? ????? ??????".
[26]
???? ???? ???? ????? ????? ?????? ????? ???? ???? ??????, ?? ?? ??? ?????? ?????? ???? ????? ??????.
[27]
????
??"?
??? ???? ???? ????? ?? ?? ?? ????? ????? ???? ????? ?
??? ?????
???? ??? ??????.
[28]
????????, ???? ???? ????? "???? ?????? ????? ????????? ?????? ?????", ???? ???? ?????? ???
????? ?????? ??????
???? ????? ?? ????? ???? ???? ????? ??? ??? ????? ??? ???????, ??? ??????? ?????? ???? ???? ????? ?????, ????? ????? ???? ????? ????? ?????? ???? ?????? ?????? ??? ????? ??????? ?????.
[28]
?????????? ?????? ?????? ??????
[
????? ??? ????
|
?????
]
?????? ??????? ??? ?????
??????????
.
[17]
??????
???? ???????
?? ???? ???? ?????? ???? ????? ?? ??? ??? ????????????? ?????? ?????? ???????.
[29]
???? ?????????? ???? ?? ???? ??????? ?? ?????????????? ??????? ??????? ????, ???? ???? ?????? ?????
????? ????'
???????? ?????? ?? ????? ????????? ???? ?????? ???? ????????.
[30]
??????? ???????
??
???? ??????
????? ????? ????? ?????? ?????????????? ??????? ???? ??? ??? ??? ???? ????? ?????? ??????? ??????. ??????? ???? ?? ????? ?????? ????????????? ????? ?????? ????? ??????? ???? ??? ??????? ??????? ???????. ??????? ???????? ?????? ?????? ?????? ????? ?????? ?????? ????? ?????? ???? ????? ???? ?????? ??????? ?? ???????????. ????
1954
????? ??????? ??????
?
?????'?
????? ?
????? ?????
????? ???? ????? ???? ??? ??????????? ???? ??????
??? ?????
?????? ??'
????? ????
. ?????? ?? ??? ??? ???? ?????? ????????????? ??????? ?? ??? ???? ???????.
?????? ?????? ?????? ???? ????? (PPS) ??????
[
????? ??? ????
|
?????
]
- ??? ????? ?
?????? ???? ?????
???? ?????? ??????? ??? ????? ???? ????? ?????? ????? ????? ???? ????, ????? ???? ???? ???? ??????? ??????? ??????, ????? ???????, ????? ?????? ?????? ?????? ?????? ?????? ?? ??????? ???? (???? ????). ???? ?????? ???? ????????, ????? ?????? ???? ?????? ?????? ?????? ?????? ???? ??????.
[31]
[32]
[33]
??? ?????? ???? ???? ????? ????? ????? ?????? ?????-?????. ?????? ???? ?????? ??????? ???? ??? ?????? ??????? ??????? ???????. ??? ??? ????? ????? ?????? ?????????? ?????? ???? ???? ??????? ??? ????? ??????????, ????? ??????, ??????????, ??????? ??????, ??????????, ????? ????, ????? ????????? ?? ??????? ??????? ????.
?????? ??????? ????? ?? ??? ?????? ?????? ?????? ?????????. ?????? ??????? ???? ????? ????????? ?????? ????? ??? ??? ???? ??????. ?????? ??????? ????? ????? ???? ????-?????, ?? ?? ?????? ??????? ??????? ??????????? ??????? ???????? ??????? ??????? ????????: ????? ????? ????????? ???????. ????? ????? ????????? ???????. ????? ????????????? ?? ?????? ???????. ????? ????? ?????? ?? ????? ???? ?????? ????? ????? ????.
?????? "Global Eradication of Poliomyelitis", ????? ???
????? ??????? ??????
,
?????
?
??????
???? ?????? ????? ????? ?????. ?????? ?????? ???? ?? ????? ????? ????? ?? ???? 2018.
[34]
???? ???????? ??? ????? ????? ????? ????? ??????? ?? ???????? ???? ???????, ???? ??? ?? ??? ???. ??? ??????? ????
??????
?
??????
. ??????? ??? ??????? ??????? ???????? ?????? ????? ?? ???????? ?????? ?? ??????.
[35]
[36]
- ???? "
????? ?????
", ????
?????????
- ?? ?????,
???? ????? ???? ?????? ???? ????? ????
, ????
?????
, 9 ????? 2004
- The Man in the Iron Lung
, ????? ????? "Mitch Summers", ????
??????
(????: 5:21)
- ???? ??
????? ?????" OR "?????
??????
??????? ???????
- ????? ?????? ???? ??????
- ????? ??? ????? ????? (?????)
- ????? ??????
,
60 ??? ???? ???? ??????? ???? ?? ????? ???? ??????. ???????? ???? ?????
, ????
????
, 28 ??????? 2009
- ????? ?????
, ??? ???????
- ????? - ????? ?????
, ????
?? ????
- ???? ????,
??"? ?-1950: ???? ????? ???? ?? ??????
, ????
ynet
, 2 ??????? 2013
- ????? ????? (????? - Polio)
???? ???? ???????
- ???? ?????-???
,
?????????? //
??????? ??????: ?? ?? ????? ???? ?? ???? ????? ??????
, ????
TheMarker
, 28 ??????? 2013
- ????? ??????? ??????
, ??????? ???????? ??
Associated Press
, ????? 1955
- ????? ????? ??? ?????
?????? ????? ????,
???? ???
,
?????? ???????
, 1956
(????? 1:27)
- ?? ????? ????? ?????? ?? ???? ?????
, ?
????
"???????" ??
??????? ???????
, 24.06.2018
- ????? ?????
, ????
??????????? ????????
(???????)
- ????? ?????
, ?? ??? ?
?????? ???????
- ^
????? ?????
???? polio eradication.
- ^
????? ???? ?? ???? ?????
,
????
, 1 ???? 1955
- ^
Aylward R (2006). "Eradicating polio: today's challenges and tomorrow's legacy".
Ann Trop Med Parasitol
.
100
(5?6): 401?13.
doi
:
10.1179/136485906X97354
.
PMID
16899145
.
- ^
????? ???? ?????
, ????
???? ????? ????
- ^
????? ????-?????
, ????
???? ????? ????
- ^
Polio Now
,
Global Polio Eradication Initiative
- ^
|,
????? ????? ???? ????? ????? ?????? ?????
,
???
, 14 ???? 1954
- ^
Holocaust Remembrance: Sharing Dr. Ervin Adam’s story
, Baylor College of Medicine
- ^
Adam Ervin
, Zahrani?ni ?lenove U?ene spole?nosti
- ^
?kovranek V., ?a?ek K., Vonka V., Adam E., Adamova V., Burian V., Vojtova H, Field trial with Sabin’s live polio vaccine in Czechoslovakia.,
Proc. First Int. Conference on live poliovirus vaccine
, 1960, ??' 530-571
- ^
Adam E., Adamova V., ?a?ek K., Surveillance of cases of CNS diseases in Czechoslovakia. ,,
Proc. European Assoc.of Poliomyelitis and Assoc. Dis. Vol VIII.
, 1962, ??' 229-239
- ^
Konstantin Chumakov, Christine S. Benn, Peter Aaby, Shyamasundaran Kottilil, Robert Gallo,
Can existing live vaccines prevent COVID-19?
,
science
, 12 Jun 2020:
- ^
1
2
3
4
????? ????? (?????)
, ???? ????? ????
- ^
??? ??????,
70 ??? ???? ???????: ?????? ????? ?????? ?????? ???? ??????
, ????
?????
, 11 ???? 2020
- ^
????? ????,
???? ????? ??????: ????? ???? ???????, 1949-1956
,
?????? ?????? ?????
??? 34, 2020, ??' 180
- ^
????? ????? (????? - Polio) - ????????? ????? ??????
, ????
???? ???????
- ^
1
2
????? ????,
??????????? ????? ????? ?????? 1950?1957
, ???? ?????? ?????? ???????????
- ^
????? ????
,
????? ????? ?????? ????
,
????
, 14 ?????? 1958
- ^
????? ????? ????? ???? ?????? ??? ????
, ????
ynet
, 24 ??????? 2005
- ^
????? ??????: ?? ?? ????? ???? ?? ?????? ??? ?????
, ???? ?
????
?, 5 ??????? 2013
- ^
?? ???
,
???? ??????? ????? ?? ????? ???? ????? ?????? ?????? ??? ????
, ????
????
, 9 ??????? 2013
- ^
?"? ???? ??,
???????: ???? ????? ???? ?????? ??? ?? ???????
, ????
ynet
, 6 ???? 2022
- ^
???? ????? ???-???
,
??????? ??????: ???? ?????? ????? ????? ?????? ????? ????
, ????
????? ????
, 17 ???? 2022
- ^
???? ???????,
?? ????? ??? ???? ????: ????? ??????? ?????? ?????? ?? ??????
, ????
????? 13
, 18 ??????? 2022
- ^
??? ?????,
????? ??? ??????
, ???? ???? ???????, 18.03.2024
- ^
??? ????? ?????? ?????
, ????"?-2007
- ^
??"? 273/10 ??? ??????? ?' ??? ???? ????? ?????? ???????
- ^
1
2
??"? 10771/07 ????? ??????? ?' ????? ?????? ?????
, ??? ???? ?? ?????
?????? ???
- ^
????? ????,
?????????????? ??????? ????
, ???? ?????? ?????? ???????????
- ^
??? ??????, ???? ????,
???? ??? ??????? ????? ??????, ?????.
, 2002, ??' 39-51
- ^
????? ?????
, ???? ????? ?????? ????
- ^
????? ???? ?????
, ???? ??? ????? ???? ?? ??????
- ^
????? ????-????? ??????? (PPS)
, ???? ???? ?? ?????
- ^
Polio eradication and endgame timeline
- ^
The Surge
- ^
Polio emergency in Nigeria
- ^
????? ??????