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Orphanet: Severe acute respiratory syndrome
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Severe acute respiratory syndrome

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Disease definition

A rare pulmonary disease induced by SARS-CoV coronavirus infection, with a reported incubation period varying from 2 to 7 days. Patients present flu-like symptoms, including fever, malaise, myalgia, headache, diarrhoea, and rigors. Dry, nonproductive, cough and dyspnea are frequently reported. Severe cases evolve rapidly, progressing to respiratory distress and failure, requiring intensive care. Mortality rate is 10%. The disease appeared in 2002 in southern China, subsequently spreading in 2003 to 26 countries. Reported human-to-human transmission occurred in Toronto (Canada), Hong Kong Special Administrative Region of China, Chinese Taipei, Singapore, and Hanoi (Viet Nam).

ORPHA:140896

Classification level: Disorder

Synonym(s):
  • SARS
  • SARS-1

Prevalence: Unknown

Inheritance: Not applicable

Age of onset: All ages

ICD-10: U04.9

ICD-11: 1D65

UMLS: C1175175

MeSH: D045169

GARD: 9237

MedDRA: 10061982

A summary on this disease is available in Francais (2020) Espanol (2020) Deutsch (2020) Italiano (2020) Portugues (2020) Nederlands (2020)
Detailed information
General public
Article for general public
Francais (2015) - Minist Sante et Prevention
Disease review articles
Review article
English (2014) - ECDC

Logo ERN: produced/endorsed by ERN(s) Logo FSMR: produced/endorsed by FSMR(s)

Additional information

Further information on this disease

Patient-centred resources for this disease

Research activities on this disease

Specialised Social Services

Newborn screening

The documents contained in this website are presented for information purposes only. The material is in no way intended to replace professional medical care by a qualified specialist and should not be used as a basis for diagnosis or treatment.