??????? ??????????????? ?????????????????? ???????.
?????????? ???????
??????????
?????? ??????????? ???????? ????????????????????? ????????? ??? ?????? ??????-
???????
???????????? ??????????? ??????????. ??? ????? ???? ???????? ??? ?????????? ????
??????
(Penam) ??????? ??????????? ??? ???????????? ?????????? ??????????? ??????????????. ????
????????????? ?????????
R-C
9
H
11
N
2
O
4
S ?????. ????? R ?????????? ?????? ?????????????.
??????
[
????
]
???????????? ??????????????? ???????????????? ???
???????????? ????????
???????????. ??? ????????????? 1928 ??? ???????????. ???????, ??? ???????????? ??? ?????????? ??????????????? ????? ????? ??????????, ??????????????? ?????????????
???????? ????????? ??????
(Howard Walter Florey) ???????????.
???????, ???????????????
???????????? ????????? ???????
?????? ??????? ?????? ??????????????????. ??? ??????? ????? ???????? 1875 ??? ??????????????. ???????
???? ????????
(John Tyndall) ??????? ??? ????? ????????? ???? ??? ???????????? (Royal Society) ???????????????.
????????? ????????????
??????? 1897 ??? ??????? ???? ??????? ??????????? ??? ??????? ??????????????. ????? ???? ?????????? ??????????
??????? ????????
???? ??????????????????.
??? ??????????
[
????
]
|
---|
??????? ??? ????????????????/
???????
/???? ??? ???????
(
???????????
-?)
| ???? ???
| |
---|
????????????? ???
|
- ????????? ???????????? ?????? (Eosinophilic esophagitis)
|
---|
|
---|
???????? ??? ????????????????/
???????????-???? ??????-?????????????? ????????????
- ???????????-???
- ???????????-??
| ???? ???
|
???????????? ?????????? ?????????? ????
|
---|
????????????? ???
| ???????????? ?????
(Cytotoxicity)
|
- ????????????? ?????????? ?????????? ?????????
- Idiopathic thrombocytopenic purpura
- Bullous pemphigoid
- ???? ?????????????? (Pemphigus vulgaris)
- ????? ????????? (Rheumatic fever)
- Goodpasture's syndrome
- Guillain?Barre syndrome
|
---|
??????? ???/?????
| |
---|
|
---|
|
---|
???????? ??? ????????????????
[?????????????? ?????? (Immune complex)]
| ???? ???
|
- Henoch?Schonlein purpura
- ?????????????? ??? ?????? (Hypersensitivity vasculitis)
- ????????????? ??????? ????? (Reactive arthritis)
- Farmer's lung
- Post-streptococcal glomerulonephritis
- ????? ???????? (Serum sickness)
- ?????? ???? [Arthus reaction]
|
---|
????????????? ???
| |
---|
|
---|
???????? ??? ????????????????/???? ?????????
(
?? ???????
)
| ???? ???
|
- Allergic contact dermatitis
- Mantoux test
|
---|
????????????? ???
| |
---|
Graft-versus-host disease
|
- Transfusion-associated graft versus host disease
|
---|
|
---|
?????????/
??????
| ???? ???
|
- ?????????????? ????????? ?????? (Hypersensitivity pneumonitis)
- Allergic bronchopulmonary aspergillosis
- ?????? ??????? ???????????
- Latex allergy (I+IV)
|
---|
????????????? ???
|
- ??????????? ????????????????? (Sjogren's syndrome)
- ????????????? ???????? ??????
- Autoimmune polyendocrine syndrome
- Autoimmune adrenalitis
- ???????? ????????????? ????
|
---|
|
---|