From Simple English Wikipedia, the free encyclopedia
Frontotemporal dementia
(
FTD
) is the clinical presentation of
frontotemporal lobar degeneration
. It is characterized by progressive
neuronal
loss predominantly involving the
frontal
or
temporal lobes
, and typical loss of over 70% of
spindle neurons
, while other neuron types remain intact.
[1]
Second only to
Alzheimer's disease
(AD) in prevalence, FTD accounts for 20% of young-onset dementia cases.
[2]
Common signs and symptoms include significant changes in social and personal behavior, apathy, blunting of emotions, and deficits in both expressive and receptive language.
