Considerable evidence now implicates elevated expression and/or activity of Src in cancer
development. In cells, endogenous Src is switched from an inactive to an active state by a …

The Cyclin D-Cdk4,6/INK4/Rb/E2F pathway plays a key role in controlling cell growth by
integrating multiple mitogenic and antimitogenic stimuli. The components of this pathway are …

The p53 tumor suppressor gene plays an important role in preventing cancer development,
by arresting or killing potential tumor cells. Mutations within the p53 gene, leading to the loss …

Objective: Venous thromboembolic events (VTE) are potentially preventable causes of
morbidity and mortality after injury. We hypothesized that the current clinical incidence of VTE is …

… by O- 1602 we performed neutrophil chemotactic assays. O- 1602 concentration-dependently …
The inhibitory effect of O- 1602 was preserved in neutrophils from CB 1 /CB 2 double …

There has been a remarkable change in the epidemiology of adenocarcinoma of the
esophagogastric junction (AEG) in the western world over the past decades. Previously rare, it is …

With their legal personhood, permanent capital, transferable shares, separation of ownership
and management, and limited liability, the Dutch and English colonial trading companies …

Seasonal and annual temperature reconstructions derived from western North American
semi-arid site tree-ring chronologies are used to examine the possible spatial response of …

The purpose of this book is to give a survey of the role played by the Dutch East India Company
in the porcelain trade. Porcelain of Chinese and Japanese provenance, but not that only …

Russia, Mongolia, China : being some record of the relations between them from the beginning
of the XVIIth century to the death of the Tsar Alexei Mikhailovich AD 1602 -1676, rendered?…