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????? :	Infectious diseases

??????????? ?? ??????????? ???????? ?????? ?????????? ?????? ?? ?????? ???? ?? ??? ?? ??? ???? ??????? ???????? ???????????? (?? ???????? ?????? ?????) ?? ??????????? ????? ????? ^[?] ?? ??? ??? ????? ??????? ???? ???? ????: ?????????? (???????), ?????????????? (????????? ?????? ??? ???????), ?? ?????? ??????????? (????? ????? ???????????? ????????)? ^[?] ???????????? ?????? ?????? ???? ?????? ??? ???????????????? ????, ??? ? ????? ?????? ???? ??????, ? ?????? ????????????? ?????? ?????? ?????? ???? ?????? ? ??????? ????? ????, ??? ???? ??? ?? ????, ? ???? (??????) ? ????? ???????? ?????? ^[?]^[?]

?????????? ???? ??????? ???????? ?? 20 ????? ??? ????????? ?????? ????? ?????? ^[?] ????? ????????? ????? ???????: ?????, ??????, ?? ??????, ? ???????? ^[?] ????????? ?????????????????? ????? ???? ?????? ????????? ????? ???? ??????? ^[?] ?? ????????, ?????? ????? ????? ??? ????????????? ??? ???? ??????? ^[?]

??????? ???? ??????? ??????? ????? ????? ?????????????? ???? ?????? ?????? ???? ??????? ^[?] ???? ????????? ???????? ??????? ???? ??????? ???? ?????? ? ?? ??? ?? ???? ???? ?? ??? ?????? ?????????? ????? ????? ????? ???????? ^[?] ??? ?????? ????, ???????? ?? ???????, ? ????????? ???????? ?????? ???? ????? ????? ????? ?????? ? ??? ???????? ??????? ^[?] ?????? ????? ???? ?????? ???? ????? ???? ???????? ????????? ????? ???????: ???????? ???????????? ?? (liposomal amphotericin B) , ^[?] ??????????????? ????????????? (pentavalent antimonials) ? ??????????? (paromomycin) ?? ??????, ^[?] ? ???????????? (miltefosine) ? ^[?] ?????????? ????? ????, ???????????, ??????????? (fluconazole) , ?? ???????????? (pentamidine) ?????????? ??? ??????? ^[?]

??? ????? 98 ????? ??? ???? 1 ???? 20 ??? ????? ^[?] ???????? ???? ^[?] ???????? ???? ???? 20 ??? ???? ????????? ???????? ^[?] ? 20 ???? 50 ???? ?????????? ?????? ???? ????? ^[?]^[?] ?????, ???????, ?????? ??? ???? ???????, ? ??????? ??????? ???? 20 ???? ???????? ?? ??? ?????? ????? ???? ????????? ??????? ^[?]^[?] ????? ????????? ?????? ?? ?? ????? ??????? ???? ???? ????????? ??? ??????? ????? ?? ^[?] ?? ??? ????? ? ????, ??????????, ?????, ???????, ??????? ??????? ???? ???? ??????????? ??? ????? ????? ^[?]

?????????? [ ??????? ????????? ]

↑ ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? "Leishmaniasis Fact sheet N°375" , World Health Organization , ????? ???? , ?????? ????? ?? ????????? ???? ?
↑ ^?.? ^?.? ^?.? ^?.? ^?.? ^?.? Barrett, MP; Croft, SL (????), "Management of trypanosomiasis and leishmaniasis.", British medical bulletin 104 : 175?96, ????? : 10.1093/bmb/lds031 , ???????? 23137768 , ?????? 3530408 ?
↑ ^?.? ^?.? Sundar, S; Chakravarty, J (Jan ????), "Leishmaniasis: an update of current pharmacotherapy.", Expert opinion on pharmacotherapy 14 (1): 53?63, ????? : 10.1517/14656566.2013.755515 , ???????? 23256501 ?
↑ Dorlo, TP; Balasegaram, M; Beijnen, JH; de Vries, PJ (Nov ????), "Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis.", The Journal of antimicrobial chemotherapy 67 (11): 2576?97, ????? : 10.1093/jac/dks275 , ???????? 22833634 ?
↑ Minodier, P; Parola, P (?? ????), "Cutaneous leishmaniasis treatment.", Travel medicine and infectious disease 5 (3): 150?8, ????? : 10.1016/j.tmaid.2006.09.004 , ???????? 17448941 ?
↑ "Leishmaniasis Magnitude of the problem" , World Health Organization , ?????? ????? ?? ????????? ???? ?
↑ Lozano, R (Dec ??, ????), "Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010.", Lancet 380 (9859): 2095?128, ????? : 10.1016/S0140-6736(12)61728-0 , ???????? 23245604 ?
↑ Ejazi, SA; Ali, N (Jan ????), "Developments in diagnosis and treatment of visceral leishmaniasis during the last decade and future prospects.", Expert review of anti-infective therapy 11 (1): 79?98, ????? : 10.1586/eri.12.148 , ???????? 23428104 ?

[WHO2014-1] ?.?? ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? ^?.?? "Leishmaniasis Fact sheet N°375" , World Health Organization , ????? ???? , ?????? ????? ?? ????????? ???? ?

[Barrett2012-2] ?.? ^?.? ^?.? ^?.? ^?.? ^?.? Barrett, MP; Croft, SL (????), "Management of trypanosomiasis and leishmaniasis.", British medical bulletin 104 : 175?96, ????? : 10.1093/bmb/lds031 , ???????? 23137768 , ?????? 3530408 ?

[Sun2013-3] ?.? ^?.? Sundar, S; Chakravarty, J (Jan ????), "Leishmaniasis: an update of current pharmacotherapy.", Expert opinion on pharmacotherapy 14 (1): 53?63, ????? : 10.1517/14656566.2013.755515 , ???????? 23256501 ?

[Dor2012-4] Dorlo, TP; Balasegaram, M; Beijnen, JH; de Vries, PJ (Nov ????), "Miltefosine: a review of its pharmacology and therapeutic efficacy in the treatment of leishmaniasis.", The Journal of antimicrobial chemotherapy 67 (11): 2576?97, ????? : 10.1093/jac/dks275 , ???????? 22833634 ?

[Min2007-5] Minodier, P; Parola, P (?? ????), "Cutaneous leishmaniasis treatment.", Travel medicine and infectious disease 5 (3): 150?8, ????? : 10.1016/j.tmaid.2006.09.004 , ???????? 17448941 ?

[Mag-6] "Leishmaniasis Magnitude of the problem" , World Health Organization , ?????? ????? ?? ????????? ???? ?

[Loz2012-7] Lozano, R (Dec ??, ????), "Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010.", Lancet 380 (9859): 2095?128, ????? : 10.1016/S0140-6736(12)61728-0 , ???????? 23245604 ?

[8] Ejazi, SA; Ali, N (Jan ????), "Developments in diagnosis and treatment of visceral leishmaniasis during the last decade and future prospects.", Expert review of anti-infective therapy 11 (1): 79?98, ????? : 10.1586/eri.12.148 , ???????? 23428104 ?

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