????? ???

????? ??? ?? ?????? ?? ??? ??? ??? ??????? . ?????? ?????? ??? ??? ???? ?????? ?????? ???????? ????? ????? ?? ???? ????? ????. ????? ??? ??????? ???? ??????????? ???????.

?? ?????????? [ ????? ??? ???? | ????? ]

??? ??? ??????, ????? ???? ???????? ?? ????? ?? ??? . ?????? ??? ???????? ?????? ???, ?? ?? ???? ???, ??????? ??"? ? ?????? ? ????? . ?? ???? ???? ?????? : "??????? ???????? ???????" - ??????? ??????? ? ???? ?? ????? ^[1]. ??? ?? ??? ????? ? ??? ?????? : "?? ???? ??? ???? ?? ??? ????? ???? ??? ?????" ( ?????? ? ?? ).

? ????????? ?????? ??????? ????? ? ???? ??????????? ????? ???? ????, ???? ?????? ?????? ????? ?? ??? ???? ?? ?? ????. ??? ??? ???????? ? ???? , ??????? ?????????? ???? ????? ??? " ????????? " ????? ???? ???? 16.

????? ??? ??? ???? ?????? ???? ??? ????? ???? ? ????????? ??????? ?? ????? . ??????? ?? ??????? ???? ?? ?? ????? ????? ??? ???, ?? ?? ????? ???, ???? ??? ?????.

? ????????? ??????? , ?????? ???? ??????? ????? ?????? ??????? ??? ?? ????? ????.

?????? [ ????? ??? ???? | ????? ]

?-DNA ???? ????? ???? ?????? ????????. ????? ?? ????? ??? ???? ?????, ????? ??? ???? ???? ????????. ???? ?? ???????? ??????? ?????? ?????? ?? DNA ??????? ????? , ??????? ?? ????? ?? ?????????, ???? ???? ??????? ??????. ??? ????????? ??? ???? ?? ????? ??????? ?????, ?? ??? ????? ????? ????? ?????. ??? ???? ?????? ????? ????? ???? ??? ??????. ?????? ???????? ?????? ?????? ?? ???? ?????? ???? ???? ?????? ?-40?60 ?????, ??? ????? ?? ? ???? ??????? . ?????? ???? ????? ???, ???? ???? ???? ???? ???????, ???? ??? ??? ?? ???? ???? ??. ??? ?????? ??, ?? ?????? ?????? ????? ????? ?? ?????? ??? ?????? ?? ????? ????? ??????.

?? ???, ???? ????? ?? ???????? ?? ?????? ????? ?? ?? ????? ????? ???? ???? ???? ???? ????? ????? ?? ????, ?????? ?? ????? ????? ????? ????? ?? ???????? ????? ??????? ^[2]. ?????, ????? ????? ????? ?? ???????? ?? ?????? ????? ???? ????? ???? ???????, ??? ????? ?? ?????? ^[3]. ???? ???, ???? ???????? ?? ??? ???? ???? ??? ??? ??? 23 ?-74 ^[4]. ???? ????? ?? ??????, ???? ?-3% ?????? ??????? ??????, ????? ?? ?? ???? ?? ???? ^[5]. ?????, ????? ???? ??? ???????? ?? ???? ????? ?????? ???????? ???? ???? ?? ????.

?????? ???? ?-90% ?????? ???????? ?????? ?????? ?????? ?? ????? ????? ??????? , ??????? ?????? ?????? ?????? ???????? ????? ?? ????????. ?????? ???? ?? ??? ???? ?????? ????? ?? ?????? ????? ?? ?????? ??? ????? ???? ????????? ??????. ????? ????? ?? ???? ??????? ????? ?? ???? ??????? ?? ??? ??? ?????? ???? ??????? ?????? ?????? ?? ????? ??.

????? [ ????? ??? ???? | ????? ]

?????? ????? ?????? ?? ????? ????? ???? ????? ????? ???? ???? ???? ???? ????? ?? ????? ???????? ^[6]^[7]^[8]. ????? ??????? ????? ?????? ???? ?????? ?"????? ????????". ???? 2015 ????? ?? ??? ??? ?? ?????? ?????????, ?????? ?????? ??????? ?????????? ???????? ^[9]^[10].

?????? ?????????? [ ????? ??? ???? | ????? ]

????? ???????? ????? ?????? ?????, ?????? ???? ???????? , ???? ???????? ??????. ??? ??, ????? ???????? ???? ?????? ???? ????? ??? ?????? ??????? ?????? ???? ???????? ??????? ?????? ??, ?? ??? ???? ?? ????? ?????? ^[11]. ??????? ?????? ?? ?'? ???? , ??? ????????? , ???? ??? ^[12], ????? ?? ???? , ???? ?????? , ????? ???? , ?????? ?????? , ??? ???? ^[13] ? ???? ??????? ^[14].

????? ?????? [ ????? ??? ???? | ????? ]

^ ??? ?????? , ??? ?"? , ???? ?'
^ Gomes NM, Ryder OA, Houck ML, Charter SJ, Walker W, Forsyth NR, Austad SN, Venditti C, Pagel M, Shay JW, Wright WE (2011). "Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination" . Aging Cell . 10 (5): 761?768. doi : 10.1111/j.1474-9726.2011.00718.x . PMC 3387546 . PMID 21518243 .
^ Cherif H, Tarry JL, Ozanne SE, Hales CN (2003). "Ageing and telomeres: a study into organ- and gender-specific telomere shortening" . Nucleic Acids Res . 31 (5): 1576?1583. doi : 10.1093/nar/gkg208 . PMC 149817 . PMID 12595567 .
^ Renault V, Thornell LE, Eriksson PO, Butler-Browne G, Mouly V (2003). "Regenerative potential of human skeletal muscle during aging". Aging Cell . 1 (2): 132?139. doi : 10.1046/j.1474-9728.2002.00017.x . PMID 12882343 .
^ Jeyapalan JC, Ferreira M, Sedivy JM, Herbig U (2007). "Accumulation of senescent cells in mitotic tissue of aging primates" . Mech Ageing Dev . 128 (1): 36?44. doi : 10.1016/j.mad.2006.11.008 . PMC 3654105 . PMID 17116315 .
^ "Former unicorn genetics startup Human Longevity loses its horn" . 2018-12-11 . ???? ?- 26 ?????? 2018 . {{ cite web }}: ( ???? )
^ "Google's Long, Strange Life-Span Trip" . ???? ?- 26 ?????? 2018 . {{ cite web }}: ( ???? )
^ "The Anti-Aging Pill" . ???? ?- 26 ?????? 2018 . {{ cite web }}: ( ???? )
^ "New "Senolytic" Drugs Can Dramatically Increase Healthy Lifespan" .
^ ????? ????????????, ????? ???????? ?? ???? , ???? ???? ??????? ????, ‏30 ???????, 2022
^ Wallace, Benjamin ( 23 ??????? 2016 ). "An MIT Scientist Claims That This Pill Is the Fountain of Youth" . New York Magazine (???????). {{ cite news }}: ( ???? )
^ "Billionaire Peter Thiel embarks on anti-aging crusade" .
^ "These Tech Billionaires Are Determined to Buy Their Way Out of Death" . Business Insider .
^ "Zuckerberg, Brin join forces to extend life" . 20 ??????? 2013 . ???? ?- 8 ??????? 2016 . {{ cite news }}: ( ???? )

[1] ??? ?????? , ??? ?"? , ???? ?'

[2] Gomes NM, Ryder OA, Houck ML, Charter SJ, Walker W, Forsyth NR, Austad SN, Venditti C, Pagel M, Shay JW, Wright WE (2011). "Comparative biology of mammalian telomeres: hypotheses on ancestral states and the roles of telomeres in longevity determination" . Aging Cell . 10 (5): 761?768. doi : 10.1111/j.1474-9726.2011.00718.x . PMC 3387546 . PMID 21518243 .

[3] Cherif H, Tarry JL, Ozanne SE, Hales CN (2003). "Ageing and telomeres: a study into organ- and gender-specific telomere shortening" . Nucleic Acids Res . 31 (5): 1576?1583. doi : 10.1093/nar/gkg208 . PMC 149817 . PMID 12595567 .

[4] Renault V, Thornell LE, Eriksson PO, Butler-Browne G, Mouly V (2003). "Regenerative potential of human skeletal muscle during aging". Aging Cell . 1 (2): 132?139. doi : 10.1046/j.1474-9728.2002.00017.x . PMID 12882343 .

[5] Jeyapalan JC, Ferreira M, Sedivy JM, Herbig U (2007). "Accumulation of senescent cells in mitotic tissue of aging primates" . Mech Ageing Dev . 128 (1): 36?44. doi : 10.1016/j.mad.2006.11.008 . PMC 3654105 . PMID 17116315 .

[6] "Former unicorn genetics startup Human Longevity loses its horn" . 2018-12-11 . ???? ?- 26 ?????? 2018 . {{ cite web }}: ( ???? )

[7] "Google's Long, Strange Life-Span Trip" . ???? ?- 26 ?????? 2018 . {{ cite web }}: ( ???? )

[8] "The Anti-Aging Pill" . ???? ?- 26 ?????? 2018 . {{ cite web }}: ( ???? )

[9] "New "Senolytic" Drugs Can Dramatically Increase Healthy Lifespan" .

[10] ????? ????????????, ????? ???????? ?? ???? , ???? ???? ??????? ????, ‏30 ???????, 2022

[11] Wallace, Benjamin ( 23 ??????? 2016 ). "An MIT Scientist Claims That This Pill Is the Fountain of Youth" . New York Magazine (???????). {{ cite news }}: ( ???? )

[12] "Billionaire Peter Thiel embarks on anti-aging crusade" .

[13] "These Tech Billionaires Are Determined to Buy Their Way Out of Death" . Business Insider .

[14] "Zuckerberg, Brin join forces to extend life" . 20 ??????? 2013 . ???? ?- 8 ??????? 2016 . {{ cite news }}: ( ???? )

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