TAS2R43

TAS2R43
?????????????
??????? ????	TAS2R43 , T2R43, T2R52, taste 2 receptor member 43
????????? ??????	OMIM: 612668 MGI: 2681304 HomoloGene: 128798 GeneCards: TAS2R43
?????? ?? (???)
????????	???????? ? (???)
?????	132,755,125 bp
?????????? ??
?????? ??????	? G protein-coupled receptor activity ; ? signal transducer activity ; ? taste receptor activity ; ? bitter taste receptor activity ;
??????? ?????	? ????? ????? ; ? cell projection ; ? motile cilium ; ? ??? ; ? membrane ; ? ciliary membrane ; ? integral component of membrane ;
?????? ?????	? detection of chemical stimulus involved in sensory perception of bitter taste ; ? GO:0072468 ???????? ???? ; ? response to stimulus ; ? sensory perception of taste ; ? G protein-coupled receptor signaling pathway ;
	?????: ????? / ????????
?????????????
	259289
	353165
	ENSG00000255374 ; ENSG00000262612 ; ENSG00000282537
	ENSMUSG00000053217
	P59537
	Q7TQA8
	NM_176884
	NM_181276
	NP_795365
	NP_851793
	?????????
??????/?????? ?????	??????/?????? ???

??????? ????? ??? ?? ??? ?? ( ??????? : Taste receptor type 2 member 43 ) ?? ??????? ??? ?? ?? ????? ???? ?? ≪ TAS2R43 ≫ ???????? ??????. ^[?]^[?]

??? ?? ? ???????? ?? ?? ????? ????? ??? ?????.

????? [ ?????? ]

↑ ^??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000053217 - Ensembl , May 2017
↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet . 32 (3): 397?401. doi : 10.1038/ng1014 . PMID 12379855 .
↑ "Entrez Gene: TAS2R43 taste receptor, type 2, member 43" .

?????????????? ?????????. ≪ TAS2R43 ≫. ?? ????????? ?????????? ??????? ? ??????????? ?? ? ????? ????.

????? ??????? [ ?????? ]

Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem . 277 (1): 1?4. doi : 10.1074/jbc.R100054200 . PMID 11696554 .
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol . 12 (4): 366?71. doi : 10.1016/S0959-4388(02)00345-8 . PMID 12139982 .
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell . 112 (3): 293?301. doi : 10.1016/S0092-8674(03)00071-0 . PMID 12581520 .
Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet. Genome Res . 98 (1): 45?53. doi : 10.1159/000068546 . PMID 12584440 .
Fischer A, Gilad Y, Man O, Paabo S (2005). "Evolution of bitter taste receptors in humans and apes" . Mol. Biol. Evol . 22 (3): 432?6. doi : 10.1093/molbev/msi027 . PMID 15496549 .
Kuhn C, Bufe B, Winnig M, Hofmann T, Frank O, Behrens M, Lewtschenko T, Slack JP, Ward CD, Meyerhof W (2005). "Bitter taste receptors for saccharin and acesulfame K.". J. Neurosci . 24 (45): 10260?5. doi : 10.1523/JNEUROSCI.1225-04.2004 . PMID 15537898 .
Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates" . Genetics . 170 (1): 313?26. doi : 10.1534/genetics.104.037523 . PMC 1449719 . PMID 15744053 .
Behrens M, Bartelt J, Reichling C, Winnig M, Kuhn C, Meyerhof W (2006). "Members of RTP and REEP gene families influence functional bitter taste receptor expression". J. Biol. Chem . 281 (29): 20650?9. doi : 10.1074/jbc.M513637200 . PMID 16720576 .

??? ?? ?????? ??? ?????????? ??????? ???. ????????? ?? ????? ?? ?? ????????? ??? ????.

[refGRCm38Ensembl-1] ??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000053217 - Ensembl , May 2017

[2] "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[3] "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[pmid12379855-4] Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet . 32 (3): 397?401. doi : 10.1038/ng1014 . PMID 12379855 .

[entrez-5] "Entrez Gene: TAS2R43 taste receptor, type 2, member 43" .

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