SETD3

SETD3
????????? ?????
PDB	?????? ?????????????: PDBe RCSB
????? ????????? PDB
	3SMT
?????????????
??????? ????	SETD3 , C14orf154, SET domain containing 3, SET domain containing 3, actin histidine methyltransferase, hSETD3
????????? ??????	OMIM: 615671 MGI: 1289184 HomoloGene: 41748 GeneCards: SETD3
?????? ?? (???)
????????	???????? ?? (???)
?????	108,145,573 bp
?????????? ??
?????? ??????	? GO:0102674? GO:0102675 methyltransferase activity ; ? transferase activity ; ? histone methyltransferase activity (H3-K4 specific) ; ? histone-lysine N-methyltransferase activity ; ? histone methyltransferase activity (H3-K36 specific) ; ? GO:0001105 transcription coactivator activity ; ? protein-lysine N-methyltransferase activity ;
??????? ?????	? ??????????? ; ? ???? ????? ;
?????? ?????	? GO:0009373 regulation of transcription, DNA-templated ; ? positive regulation of muscle cell differentiation ; ? transcription, DNA-templated ; ? GO:0060469? GO:0009371 positive regulation of transcription, DNA-templated ; ? peptidyl-lysine methylation ; ? ???????? ???? ; ? GO:0003257? GO:0010735? GO:1901228? GO:1900622? GO:1904488 positive regulation of transcription by RNA polymerase II ; ? peptidyl-lysine dimethylation ; ? peptidyl-lysine trimethylation ; ? histone H3-K36 methylation ; ? peptidyl-lysine monomethylation ; ? histone H3-K4 methylation ; ? GO:0031497? GO:0006336? GO:0034724? GO:0001301? GO:0007580? GO:0034652? GO:0010847 chromatin organization ;
	?????: ????? / ????????
?????????????
	84193
	52690
	ENSG00000183576
	ENSMUSG00000056770
	Q86TU7
	Q91WC0
	NM_032233? NM_199123? XM_011537231? XM_011537232? XM_011537233? XM_017021699? XM_017021700? XM_047431805 XM_011537235? NM_032233? NM_199123? XM_011537231? XM_011537232? XM_011537233? XM_017021699? XM_017021700? XM_047431805
	XM_006516078? XM_006516081? XM_017315133? NM_001364266? NM_001364267? NM_001364268? NM_001364269? NM_001364270? XM_030246811? XR_003950065? XR_003950066 NM_028262? XM_006516078? XM_006516081? XM_017315133? NM_001364266? NM_001364267? NM_001364268? NM_001364269? NM_001364270? XM_030246811? XR_003950065? XR_003950066
	NP_954574? XP_005268184? XP_011535533? XP_011535534? XP_011535535? XP_011535536? XP_011535537? XP_016877188? XP_016877189? XP_016877190? XP_016877191 NP_115609? NP_954574? XP_005268184? XP_011535533? XP_011535534? XP_011535535? XP_011535536? XP_011535537? XP_016877188? XP_016877189? XP_016877190? XP_016877191
	XP_006516141? XP_006516144? XP_017170622? NP_001351195? NP_001351196? NP_001351197? NP_001351198? NP_001351199? XP_030102671 NP_082538? XP_006516141? XP_006516144? XP_017170622? NP_001351195? NP_001351196? NP_001351197? NP_001351198? NP_001351199? XP_030102671
	?????????
??????/?????? ?????	??????/?????? ???

??????? ? ???? ????? ???????? ( ??????? : SET domain containing 3 ) ?? ??????? ??? ?? ?? ????? ???? ?? ≪ SETD3 ≫ ???????? ??????. ^[?]

??? ??????? ???? ?????????????? ??? ?? ?? ?????????? ????? ????? ????????????? ??? ????. ???????? ?? ???? ????? ??? ??????? ?????? ???? ?? ????????? ??????????? ?????? ?????. ??? ????? ???????? ??? ?? ???? ?????? ?? ????? ?????????? ? ????????? ? ?????? ?????? ? ??? ????? ????? ????. ^[?]

???????? ?????? [ ?????? ]

????? [ ?????? ]

↑ ^??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000056770 - Ensembl , May 2017
↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ "Entrez Gene: SET domain containing 3" . Retrieved 2018-01-22 .
↑ https://www.nature.com/articles/s41564-019-0551-1

?????????????? ?????????. ≪ SETD3 (gene) ≫. ?? ????????? ?????????? ??????? ? ??????????? ?? ?? ??????? ????.

???? ??????? ????? [ ?????? ]

Cooper SE, Hodimont E, Green CM (2015). "A fluorescent bimolecular complementation screen reveals MAF1, RNF7 and SETD3 as PCNA-associated proteins in human cells" . Cell Cycle . 14 (15): 2509?19. doi : 10.1080/15384101.2015.1053667 . PMC 4613188 . PMID 26030842 .
Pires-Luis AS, Vieira-Coimbra M, Vieira FQ, Costa-Pinheiro P, Silva-Santos R, Dias PC, Antunes L, Lobo F, Oliveira J, Goncalves CS, Costa BM, Henrique R, Jeronimo C (2015). "Expression of histone methyltransferases as novel biomarkers for renal cell tumor diagnosis and prognostication" . Epigenetics . 10 (11): 1033?43. doi : 10.1080/15592294.2015.1103578 . PMC 4844211 . PMID 26488939 .

??? ?? ?????? ??? ?????????? ??????? ???. ????????? ?? ????? ?? ?? ????????? ??? ????.

[refGRCm38Ensembl-1] ??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000056770 - Ensembl , May 2017

[2] "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[3] "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[entrez-4] "Entrez Gene: SET domain containing 3" . Retrieved 2018-01-22 .

[5] ttps://www.nature.com/articles/s41564-019-0551-1

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