RRAGA

RRAGA
?????????????
??????? ????	RRAGA , FIP-1, FIP1, RAGA, Ras related GTP binding A
????????? ??????	OMIM: 612194 MGI: 1915691 HomoloGene: 68522 GeneCards: RRAGA
?????? ?? (???)
????????	???????? ? (???)
?????	86,495,522 bp
????? ????? RNA
	More reference expression data
?????????? ??
?????? ??????	? nucleotide binding ; ? protein homodimerization activity ; ? GTP binding ; ? phosphoprotein binding ; ? GO:0001948? GO:0016582 ????? ???????? ; ? GO:0006184 GTPase activity ; ? ubiquitin protein ligase binding ; ? protein heterodimerization activity ;
??????? ?????	? ????????? ; ? ??????? ; ? GATOR1 complex ; ? lysosomal membrane ; ? ????????? ; ? ???? ????? ; ? Gtr1-Gtr2 GTPase complex ;
?????? ?????	? cellular response to amino acid starvation ; ? ??? ????? ; ? positive regulation of cytolysis ; ? positive regulation of TORC1 signaling ; ? modulation by virus of host process ; ? cellular response to amino acid stimulus ; ? GO:0022415 viral process ; ? negative regulation of autophagy ; ? positive regulation of TOR signaling ; ? GO:0097285 ??? ??????????????? ????? ; ? protein ubiquitination ; ? regulation of macroautophagy ; ? cellular response to starvation ; ? regulation of autophagy ;
	?????: ????? / ????????
?????????????
	10670
	68441
	ENSG00000155876
	ENSMUSG00000070934
	Q7L523
	Q80X95
	NM_006570
	NM_178376
	NP_006561
	NP_848463
	?????????
??????/?????? ?????	??????/?????? ???

??????? A ?????????? ?? ???????? ????? ?? ??????? ( ??????? : Ras-related GTP-binding protein A ) ?? ??????? ??? ?? ?? ????? ???? ?? ≪ RRAGA ≫ ???????? ??????. ^[?]^[?]^[?]

????? [ ?????? ]

↑ ^??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000070934 - Ensembl , May 2017
↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ Schurmann A, Brauers A, Massmann S, Becker W, Joost HG (Dec 1995). "Cloning of a novel family of mammalian GTP-binding proteins (raga d, RagBs, RagB1) with remote similarity to the Ras-related GTPases" . The Journal of Biological Chemistry . 270 (48): 28982?8. doi : 10.1074/jbc.270.48.28982 . PMID 7499430 .
↑ Li Y, Kang J, Horwitz MS (Feb 1997). "Interaction of an adenovirus 14.7-kilodalton protein inhibitor of tumor necrosis factor alpha cytolysis with a new member of the GTPase superfamily of signal transducers" . Journal of Virology . 71 (2): 1576?82. doi : 10.1128/JVI.71.2.1576-1582.1997 . PMC 191215 . PMID 8995684 .
↑ "Entrez Gene: RRAGA Ras-related GTP binding A" .

???? ??????? ????? [ ?????? ]

Hirose E, Nakashima N, Sekiguchi T, Nishimoto T (Jan 1998). "RagA is a functional homologue of S. cerevisiae Gtr1p involved in the Ran/Gsp1-GTPase pathway". Journal of Cell Science . 111 ( Pt 1) (1): 11?21. doi : 10.1242/jcs.111.1.11 . PMID 9394008 .
Sekiguchi T, Hirose E, Nakashima N, Ii M, Nishimoto T (Mar 2001). "Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B" . The Journal of Biological Chemistry . 276 (10): 7246?57. doi : 10.1074/jbc.M004389200 . PMID 11073942 .
Sekiguchi T, Todaka Y, Wang Y, Hirose E, Nakashima N, Nishimoto T (Feb 2004). "A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D" . The Journal of Biological Chemistry . 279 (9): 8343?50. doi : 10.1074/jbc.M305935200 . PMID 14660641 .
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (Oct 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173?8. Bibcode : 2005Natur.437.1173R . doi : 10.1038/nature04209 . PMID 16189514 . S2CID 4427026 .

??? ?? ?????? ??? ?????????? ??????? ???. ????????? ?? ????? ?? ?? ????????? ??? ????.

[refGRCm38Ensembl-1] ??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000070934 - Ensembl , May 2017

[2] "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[3] "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[pmid7499430-4] Schurmann A, Brauers A, Massmann S, Becker W, Joost HG (Dec 1995). "Cloning of a novel family of mammalian GTP-binding proteins (raga d, RagBs, RagB1) with remote similarity to the Ras-related GTPases" . The Journal of Biological Chemistry . 270 (48): 28982?8. doi : 10.1074/jbc.270.48.28982 . PMID 7499430 .

[pmid8995684-5] Li Y, Kang J, Horwitz MS (Feb 1997). "Interaction of an adenovirus 14.7-kilodalton protein inhibitor of tumor necrosis factor alpha cytolysis with a new member of the GTPase superfamily of signal transducers" . Journal of Virology . 71 (2): 1576?82. doi : 10.1128/JVI.71.2.1576-1582.1997 . PMC 191215 . PMID 8995684 .

[entrez-6] "Entrez Gene: RRAGA Ras-related GTP binding A" .

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