MEFV

MEFV
????????? ?????
PDB	?????? ?????????????: PDBe RCSB
????? ????????? PDB
	2WL1 , 2MPC , 4CG4
?????????????
??????? ????	MEFV , FMF, MEF, TRIM20, Mediterranean fever, pyrin innate immunity regulator, MEFV innate immuity regulator, pyrin, PAAND
????????? ??????	OMIM: 608107 MGI: 1859396 HomoloGene: 32441 GeneCards: MEFV
?????? ?? (???)
????????	???????? ?? (???)
?????	3,535,961 bp
????? ????? RNA
	More reference expression data
?????????? ??
?????? ??????	? zinc ion binding ; ? metal ion binding ; ? GO:0001948? GO:0016582 ????? ???????? ; ? actin binding ; ? identical protein binding ;
??????? ?????	? ????????? ; ? ??????? ; ? cell projection ; ? ruffle ; ? intracellular anatomical structure ; ? microtubule associated complex ; ? autophagosome ; ? ??????? ; ? ????? ????? ; ? GO:0016023 cytoplasmic vesicle ; ? ???? ????? ; ? ???????? ;
?????? ?????	? positive regulation of cysteine-type endopeptidase activity ; ? negative regulation of interleukin-1 beta production ; ? response to interferon-gamma ; ? positive regulation of autophagy ; ? negative regulation of macrophage inflammatory protein 1 alpha production ; ? immune system process ; ? negative regulation of NLRP3 inflammasome complex assembly ; ? inflammatory response ; ? negative regulation of inflammatory response ; ? negative regulation of cytokine production involved in inflammatory response ; ? negative regulation of interleukin-12 production ; ? ?????? ????? ???? ;
	?????: ????? / ????????
?????????????
	4210
	54483
	ENSG00000103313
	ENSMUSG00000022534
	O15553
	Q9JJ26
	NM_000243 NM_001198536? NM_000243
	NM_001161791? NM_019453? XM_006522361? XM_030249188? XM_030249189 NM_001161790? NM_001161791? NM_019453? XM_006522361? XM_030249188? XM_030249189
	NP_001185465? XP_016878725 NP_000234? NP_001185465? XP_016878725
	NP_001155263? NP_062326? XP_006522424? XP_030105048? XP_030105049 NP_001155262? NP_001155263? NP_062326? XP_006522424? XP_030105048? XP_030105049
	?????????
??????/?????? ?????	??????/?????? ???

MEFV ( ??????? : MEFV ) ??? ?? ?? ?? ????? ??? ?? ???? ???? ???????? ?? ??? ≪ ?????? ≫ (Pyrin) ??????.

?????? ?? ?? ??? ≪??????????≫ ?? ?????? ?? ??? ???????? ??? ?? ???? ????????? ???? ( ???????? ? ?????????? ? ??????? ) ????? ?????? ? ?? ????? ?????? ? ?????? ?? ???????? ??? ????. ?? ???? ???????? ?????? ??????? ?????? ?? ????? ??????????? ?? ???? ?????? ?? ?? ??????? ? ?????? ???????? ????? ???? ?????. ??? ?????? ?????????? ??? ?? ????? ????? ?? ????????? ???? ?? ????? ? ?????? ?? ????? ?? ????? ??????.

???? ?????? ???? ?????? ???? ???? ????? ??? ???????? ?? ????? ???? ?????? ??? ????.

??? ?? ?? ??? ????? ????????? ???????? ?? ?? ?????? ≪????≫ ???? ???? ? ?? ??????? ?????? ????????? ?? ????????? ?? ?? ?? ???????. ^[?]

????? [ ?????? ]

↑ ^??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000022534 - Ensembl , May 2017
↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ "MEFV - Mediterranean fever" . US National Library of Medicine, National Institutes of Health, Department of Health & Human Services. 2011-04-07 . Retrieved 2011-04-14 .

?????????????? ?????????. ≪ MEFV ≫. ?? ????????? ?????????? ??????? ? ??????????? ?? ? ????? ????.

????? ?? ????? [ ?????? ]

marenostrin ?? ??????????? ?????? ????? (MeSH) ?? ????????? ??? ????? ?????? ?????? ??????

??? ?? ?????? ??? ?????????? ??????? ???. ????????? ?? ????? ?? ?? ????????? ??? ????.

[refGRCm38Ensembl-1] ??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000022534 - Ensembl , May 2017

[2] "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[3] "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[4] "MEFV - Mediterranean fever" . US National Library of Medicine, National Institutes of Health, Department of Health & Human Services. 2011-04-07 . Retrieved 2011-04-14 .

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