DCAF17

DCAF17
?????????????
??????? ????	DCAF17 , C2orf37, DDB1 and CUL4 associated factor 17, C20orf37
????????? ??????	OMIM: 612515 MGI: 1923013 HomoloGene: 65979 GeneCards: DCAF17
?????? ?? (???)
????????	???????? ? (???)
?????	71,099,142 bp
?????????? ??
?????? ??????	? GO:0001948? GO:0016582 ????? ???????? ;
??????? ?????	? integral component of membrane ; ? Cul4-RING E3 ubiquitin ligase complex ; ? ???? ; ? membrane ; ? ???? ????? ; ? ??????? ; ? ??????????? ;
?????? ?????	? ?????? ?????????? ; ? protein ubiquitination ;
	?????: ????? / ????????
?????????????
	80067
	75763
	ENSG00000115827
	ENSMUSG00000041966
	Q5H9S7
	Q3TUL7
	NM_025000? NR_028482? XM_006712768? XM_011511881? XM_011511882? XM_017004996? XM_017004999? XM_017005001? XM_047445911? XM_047445912? XM_047445913? XR_007082530 NM_001164821? NM_025000? NR_028482? XM_006712768? XM_011511881? XM_011511882? XM_017004996? XM_017004999? XM_017005001? XM_047445911? XM_047445912? XM_047445913? XR_007082530
	NM_001165981? NM_001165982? NM_198005? XM_006500339? XM_006500340? XR_374535? XR_001783197? XM_030252168 NM_001165980? NM_001165981? NM_001165982? NM_198005? XM_006500339? XM_006500340? XR_374535? XR_001783197? XM_030252168
	NP_079276? XP_006712830? XP_006712831? XP_011510183? XP_011510184? XP_016860484? XP_016860485? XP_016860486? XP_016860487? XP_016860488? XP_016860489? XP_016860490? XP_016860491 NP_001158293? NP_079276? XP_006712830? XP_006712831? XP_011510183? XP_011510184? XP_016860484? XP_016860485? XP_016860486? XP_016860487? XP_016860488? XP_016860489? XP_016860490? XP_016860491
	NP_001159453? NP_001159454? NP_932122? XP_006500402? XP_030108028? XP_036018544? XP_036018545 NP_001159452? NP_001159453? NP_001159454? NP_932122? XP_006500402? XP_030108028? XP_036018544? XP_036018545
	?????????
??????/?????? ?????	??????/?????? ???

?????? ?????? ?? ????? ?? DDB1 ? CUL4 ( ??????? : DDB1 and CUL4 associated factor 17 ) ?? ??????? ??? ?? ?? ????? ???? ?? ≪ DCAF17 ≫ ??????? ??????.

??? ??????? ?? ??????? ???????? ??????? ?? ???? ???. ??? ?? ?? ?????????? ??? ??????? ???? ?? ???? ????? ???????-?????? ??????.

????? [ ?????? ]

↑ ^??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000041966 - Ensembl , May 2017
↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

?????????????? ?????????. ≪ DCAF17 ≫. ?? ????????? ?????????? ??????? ? ??????????? ?? ?? ????? ????.

????? ??????? [ ?????? ]

Bonaldo MF, Lennon G, Soares MB (1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res . 6 (9): 791?806. doi : 10.1101/gr.6.9.791 . PMID 8889548 .
Alazami AM, Schneider SA, Bonneau D, et al. (2010). "C2orf37 mutational spectrum in Woodhouse-Sakati syndrome patients". Clin. Genet . 78 (6): 585?90. doi : 10.1111/j.1399-0004.2010.01441.x . PMID 20507343 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899?903. doi : 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Alazami AM, Al-Saif A, Al-Semari A, et al. (2008). "Mutations in C2orf37, encoding a nucleolar protein, cause hypogonadism, alopecia, diabetes mellitus, mental retardation, and extrapyramidal syndrome" . Am. J. Hum. Genet . 83 (6): 684?91. doi : 10.1016/j.ajhg.2008.10.018 . PMC 2668059 . PMID 19026396 .
Lee J, Zhou P (2007). "DCAFs, the missing link of the CUL4-DDB1 ubiquitin ligase". Mol. Cell . 26 (6): 775?80. doi : 10.1016/j.molcel.2007.06.001 . PMID 17588513 .
Behrends C, Sowa ME, Gygi SP, Harper JW (2010). "Network organization of the human autophagy system" . Nature . 466 (7302): 68?76. doi : 10.1038/nature09204 . PMC 2901998 . PMID 20562859 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet . 36 (1): 40?5. doi : 10.1038/ng1285 . PMID 14702039 .
Jin J, Arias EE, Chen J, et al. (2006). "A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1". Mol. Cell . 23 (5): 709?21. doi : 10.1016/j.molcel.2006.08.010 . PMID 16949367 .

??? ?? ?????? ??? ?????????? ??????? ???. ????????? ?? ????? ?? ?? ????????? ??? ????.

[refGRCm38Ensembl-1] ??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000041966 - Ensembl , May 2017

[2] "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[3] "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

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