CagA

?? ??? ????? ?? ???? ?????
?? ??? ????? ?? ???? ?????
Identifiers
Organism	Helicobacter pylori (strain ATCC 700392 / 26695)
Symbol	CagA
UniProt	P55980

CagA ?? ???? ????? ?? ??? ????? ?? ???? ????? ???? ?? ??????? ??? ?? ??? ???? ??????? ??? ?? ???? ???????? ?????????? ?????? ????? ??????. ^[?] ?? ???? ???????? ?????????? ?????? ?? ??????? ?? ?? ???? ????? ???: ?????? ?? CagA ????? ? ?????? ?? ??????. ?? ???? ??? ?? ???????? ?????????? ?????? ?? ??????? ???? ? ???? ?? ????? ???? ????? ??? ??????? ?????. ^[?]

??? ???? ???????? ????? ????? ????? ??? ? ??? ?? ?? ?? ??? ????? ??????? CagA ?? ???? ??? ?? ?? ????? ?????????? ?????? ?? ?? ??????? ??????. ?? ?? ???? ?? ???? ???? ??? ??????? ?? ??? ????? ???? ???? ??? ???? ???? ? ???? ????????? ??????? ???????? Src (????? FYN ? LYN ) ???? ??????????? ??????? ???????. ^[?]

????? ?????? [ ?????? ]

?????????? ?????? ?? ???? ????? MALT ? ????? ???? ?? ?????? ??? ? ?????? ?????? ?? ??????? CagA ?? ?? ??? ????? ????. ^[?]

??? ??????? ?????? ?????? ?????????? ??? ? ?? ????? ????? ?????????? ? ? ?? ???? ???? ??????? ???? ??? ????. ^[?]

????? [ ?????? ]

↑ ^??? ^??? ^??? Hatakeyama, M.; Higashi, H. (2005). " Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis" . Cancer Science . 96 (12): 835?843. doi : 10.1111/j.1349-7006.2005.00130.x . PMID 16367902 .
↑ Lax, A. (2005). "Bacterial toxins and cancer ? a case to answer?". Nature Reviews Microbiology . 3 (4): 343?9. doi : 10.1038/nrmicro1130 . PMID 15806096 . S2CID 6129498 .
↑ Yamaoka Y (November 2010). "Mechanisms of disease: Helicobacter pylori virulence factors" . Nat Rev Gastroenterol Hepatol . 7 (11): 629?41. doi : 10.1038/nrgastro.2010.154 . PMC 3137895 . PMID 20938460 .

?????????????? ?????????. ≪ CagA ≫. ?? ????????? ?????????? ??????? ? ??????????? ?? ?? ???? ????.

??? ?? ?????? ??? ?????????? ??????? ???. ????????? ?? ????? ?? ?? ????????? ??? ????.

[pmid16367902-1] ??? ^??? ^??? Hatakeyama, M.; Higashi, H. (2005). " Helicobacter pylori CagA: a new paradigm for bacterial carcinogenesis" . Cancer Science . 96 (12): 835?843. doi : 10.1111/j.1349-7006.2005.00130.x . PMID 16367902 .

[pmid15806096-2] Lax, A. (2005). "Bacterial toxins and cancer ? a case to answer?". Nature Reviews Microbiology . 3 (4): 343?9. doi : 10.1038/nrmicro1130 . PMID 15806096 . S2CID 6129498 .

[3] Yamaoka Y (November 2010). "Mechanisms of disease: Helicobacter pylori virulence factors" . Nat Rev Gastroenterol Hepatol . 7 (11): 629?41. doi : 10.1038/nrgastro.2010.154 . PMC 3137895 . PMID 20938460 .

[?]

[?]

[?]