CYP2A6

CYP2A6
????????? ?????
PDB	?????? ?????????????: PDBe RCSB
????? ????????? PDB
	4RUI , 1Z10 , 1Z11 , 2FDU , 2FDV , 2FDW , 2FDY , 3EBS , 3T3Q , 3T3R , 4EJJ
?????????????
??????? ????	CYP2A6 , CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB, cytochrome P450 family 2 subfamily A member 6
????????? ??????	OMIM: 122720 MGI: 88597 HomoloGene: 85917 GeneCards: CYP2A6
?????? ?? (???)
????????	???????? ? (???)
?????	26,542,973 bp
?????????? ??
?????? ??????	? iron ion binding ; ? arachidonic acid epoxygenase activity ; ? oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen ; ? metal ion binding ; ? monooxygenase activity ; ? heme binding ; ? GO:0050602 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen ; ? enzyme binding ; ? oxidoreductase activity ; ? coumarin 7-hydroxylase activity ; ? steroid hydroxylase activity ;
??????? ?????	? organelle membrane ; ? endoplasmic reticulum membrane ; ? membrane ; ? intracellular membrane-bounded organelle ; ? ???? ?????????? ; ? cytoplasmic microtubule ; ? ????????? ;
?????? ?????	? steroid metabolic process ; ? epoxygenase P450 pathway ; ? coumarin catabolic process ; ? coumarin metabolic process ; ? organic acid metabolic process ; ? xenobiotic metabolic process ;
	?????: ????? / ????????
?????????????
	1548
	13087
	ENSG00000255974
	ENSMUSG00000005547
	P11509
	P20852
	NM_000762
	NM_007812
	NP_000753
	?/?
	?????????
??????/?????? ?????	??????/?????? ???

???????? P450 2A6 ( ??????? CYP2A6 ) ???? ?? ????? ??????? ???????? ?? ??? ?? ?????? ?????? ??? ?? ?? ????????? ?????????????? ?? ??? ??? ????. CYP2A6 ????? ???? ????? ?????????? ??????? ? ??????? ?? ??? ??? ? ?????? ?? ????????? ????? ????? ???? ???????? ? ?????? ?? ???????????? ??? ??????? ??? ????.

????? [ ?????? ]

↑ ^??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000005547 - Ensembl , May 2017
↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

?????????????? ?????????. ≪ CYP2A6 ≫. ?? ????????? ?????????? ??????? ? ??????????? ?? ?? ?? ????.

??? ?? ?????? ??? ?????????? ??????? ???. ????????? ?? ????? ?? ?? ????????? ??? ????.

[refGRCm38Ensembl-1] ??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000005547 - Ensembl , May 2017

[2] "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[3] "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

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