C21orf33

GATD3
?????????????
??????? ????	GATD3 , ES1, GT335, HES1, KNPH, KNPI, chromosome 21 open reading frame 33, C21orf33, glutamine amidotransferase like class 1 domain containing 3A, glutamine amidotransferase class 1 domain containing 3A, GATD3A, glutamine amidotransferase class 1 domain containing 3
????????? ??????	OMIM: 601659 MGI: 1351861 HomoloGene: 3416 GeneCards: GATD3
?????? ?? (???)
????????	???????? ?? (???)
?????	78,005,616 bp
????? ????? RNA
	; ;
	More reference expression data
?????????????
	8209
	28295
	ENSG00000160221
	ENSMUSG00000053329
	F2Z2Q0 ; H7C1F6
	Q9D172
	NM_198155? NM_001320383? NM_001320384? NR_135220? XM_017028479 NM_004649? NM_198155? NM_001320383? NM_001320384? NR_135220? XM_017028479
	NM_001364646 NM_138601? NM_001364646
	NP_001307313? NP_004640? NP_937798? XP_016883968? XP_024307901? NP_001350687? NP_001350689? NP_001350690? XP_006723964? XP_006723965? XP_006723966? XP_006723967? XP_011544383? XP_016884003? XP_016884005? XP_016884006? XP_024307910 NP_001307312? NP_001307313? NP_004640? NP_937798? XP_016883968? XP_024307901? NP_001350687? NP_001350689? NP_001350690? XP_006723964? XP_006723965? XP_006723966? XP_006723967? XP_011544383? XP_016884003? XP_016884005? XP_016884006? XP_024307910
	NP_001351575 NP_613067? NP_001351575
	?????????
??????/?????? ?????	??????/?????? ???

??????? ??????? ES1? ???????????? ( ??????? : ES1 protein homolog, mitochondrial ) ?? ??????? ??? ?? ?? ????? ???? ?? ≪ C21orf33 ≫ ???????? ??????. ^[?]^[?]^[?]

????? [ ?????? ]

↑ ^??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000053329 - Ensembl , May 2017
↑ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
↑ Scott HS, Chen H, Rossier C, Lalioti MD, Antonarakis SE (Jun 1997). "Isolation of a human gene (HES1) with homology to an Escherichia coli and a zebrafish protein that maps to chromosome 21q22.3". Hum Genet . 99 (5): 616?23. doi : 10.1007/s004390050416 . PMID 9150728 .
↑ Lafreniere RG, Rochefort DL, Kibar Z, Fon EA, Han F, Cochius J, Kang X, Baird S, Korneluk RG, Andermann E, Rommens JM, Rouleau GA (Mar 1997). "Isolation and characterization of GT335, a novel human gene conserved in Escherichia coli and mapping to 21q22.3". Genomics . 38 (3): 264?72. doi : 10.1006/geno.1996.0627 . PMID 8975701 .
↑ "Entrez Gene: C21orf33 chromosome 21 open reading frame 33" .

?????????????? ?????????. ≪ C21orf33 ≫. ?? ????????? ?????????? ??????? ? ??????????? ?? ? ????? ????.

????? ?? ????? [ ?????? ]

???? ???? C21orf33 ?????? ? ????? ?????? ??? C21orf33 ?? ?????? ?????? ???? ??? ??????? ?????????? ????? ???? .
???? ???? HES1 ?????? ? ????? ?????? ??? HES1 ?? ?????? ?????? ???? ??? ??????? ?????????? ????? ???? .

???? ??????? ????? [ ?????? ]

Hochstrasser DF, Frutiger S, Paquet N, et al. (1993). "Human liver protein map: a reference database established by microsequencing and gel comparison". Electrophoresis . 13 (12): 992?1001. doi : 10.1002/elps.11501301201 . PMID 1286669 .
Nagamine K, Kudoh J, Minoshima S, et al. (1996). "Isolation of cDNA for a novel human protein KNP-I that is homologous to the E. coli SCRP-27A protein from the autoimmune polyglandular disease type I (APECED) region of chromosome 21q22.3". Biochem. Biophys. Res. Commun . 225 (2): 608?16. doi : 10.1006/bbrc.1996.1218 . PMID 8753807 .
Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags". Genome Res . 6 (9): 807?28. doi : 10.1101/gr.6.9.807 . PMID 8889549 .
Kudoh J, Nagamine K, Asakawa S, et al. (1997). "Localization of 16 exons to a 450-kb region involved in the autoimmune polyglandular disease type I (APECED) on human chromosome 21q22.3". DNA Res . 4 (1): 45?52. doi : 10.1093/dnares/4.1.45 . PMID 9179495 .
Nagamine K, Kudoh J, Minoshima S, et al. (1997). "Genomic organization and complete nucleotide sequence of the human PWP2 gene on chromosome 21". Genomics . 42 (3): 528?31. doi : 10.1006/geno.1997.4761 . PMID 9205129 .
Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21". Nature . 405 (6784): 311?9. doi : 10.1038/35012518 . PMID 10830953 .
Yan B, Raben N, Plotz P (2002). "The human acid alpha-glucosidase gene is a novel target of the Notch-1/Hes-1 signaling pathway". J. Biol. Chem . 277 (33): 29760?4. doi : 10.1074/jbc.M204721200 . PMID 12065598 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899?903. doi : 10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Shin JH, Weitzdoerfer R, Fountoulakis M, Lubec G (2004). "Expression of cystathionine beta-synthase, pyridoxal kinase, and ES1 protein homolog (mitochondrial precursor) in fetal Down syndrome brain". Neurochem. Int . 45 (1): 73?9. doi : 10.1016/j.neuint.2003.12.004 . PMID 15082224 .
Hartman J, Muller P, Foster JS, et al. (2005). "HES-1 inhibits 17beta-estradiol and heregulin-beta1-mediated upregulation of E2F-1". Oncogene . 23 (54): 8826?33. doi : 10.1038/sj.onc.1208139 . PMID 15467735 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121?7. doi : 10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .

??? ?? ?????? ??? ?????????? ??????? ???. ????????? ?? ????? ?? ?? ????????? ??? ????.

[refGRCm38Ensembl-1] ??? ^??? ^??? GRCm38: Ensembl release 89: ENSMUSG00000053329 - Ensembl , May 2017

[2] "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[3] "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .

[pmid9150728-4] Scott HS, Chen H, Rossier C, Lalioti MD, Antonarakis SE (Jun 1997). "Isolation of a human gene (HES1) with homology to an Escherichia coli and a zebrafish protein that maps to chromosome 21q22.3". Hum Genet . 99 (5): 616?23. doi : 10.1007/s004390050416 . PMID 9150728 .

[pmid8975701-5] Lafreniere RG, Rochefort DL, Kibar Z, Fon EA, Han F, Cochius J, Kang X, Baird S, Korneluk RG, Andermann E, Rommens JM, Rouleau GA (Mar 1997). "Isolation and characterization of GT335, a novel human gene conserved in Escherichia coli and mapping to 21q22.3". Genomics . 38 (3): 264?72. doi : 10.1006/geno.1996.0627 . PMID 8975701 .

[entrez-6] "Entrez Gene: C21orf33 chromosome 21 open reading frame 33" .

[?]

[?]

[?]

[?]

[?]

[?]