?? ?????????? ????????? ????
??????? ??????? ??????? ?????????
(
???????
:
Progressive ankylosis protein homolog
) ??
???????
??? ?? ????? ????
??
≪
ANKH
≫ ???????? ??????.
[?]
[?]
[?]
?? ?????? ?????? ????? ??
??????? ???????????
?? ????? ??? ? ???
?????????
?? ??????? ????? ??????. ??? ?? ??? ?? ?????? ??? ????
?????? ????
????????? ? ???? ????? ?? ???? ? ????? ?????? ???????? ? ????? ????? ??????.
????????
??? ?? ?? ????? ?? ????? ??? ???????????? ? ?????? ?????
????????????
???? ??? ? ???? ????? ???? ?????? ???? ??????? ? ??????? ???? ??????? ???? ?? ????? ??
??????
????.
[?]
???????? ??????
[
??????
]
- ↑
???
???
???
GRCm38: Ensembl release 89: ENSMUSG00000022265
-
Ensembl
, May 2017
- ↑
"Human PubMed Reference:"
.
National Center for Biotechnology Information, U.S. National Library of Medicine
.
- ↑
"Mouse PubMed Reference:"
.
National Center for Biotechnology Information, U.S. National Library of Medicine
.
- ↑
Ho AM, Johnson MD, Kingsley DM (Jul 2000). "Role of the mouse ank gene in control of tissue calcification and arthritis".
Science
.
289
(5477): 265?70.
doi
:
10.1126/science.289.5477.265
.
PMID
10894769
.
- ↑
Williams CJ, Zhang Y, Timms A, Bonavita G, Caeiro F, Broxholme J, Cuthbertson J, Jones Y, Marchegiani R, Reginato A, Russell RG, Wordsworth BP, Carr AJ, Brown MA (Sep 2002).
"Autosomal dominant familial calcium pyrophosphate dihydrate deposition disease is caused by mutation in the transmembrane protein ANKH"
.
Am J Hum Genet
.
71
(4): 985?91.
doi
:
10.1086/343053
.
PMC
419998
.
PMID
12297989
.
- ↑
???
???
"Entrez Gene: ANKH ankylosis, progressive homolog (mouse)"
.
????? ???????
[
??????
]
- Williams CJ (2003). "Familial calcium pyrophosphate dihydrate deposition disease and the ANKH gene".
Current Opinion in Rheumatology
.
15
(3): 326?31.
doi
:
10.1097/00002281-200305000-00023
.
PMID
12707589
.
- Netter P, Bardin T, Bianchi A, et al. (2005). "The ANKH gene and familial calcium pyrophosphate dihydrate deposition disease".
Joint Bone Spine
.
71
(5): 365?8.
doi
:
10.1016/j.jbspin.2004.01.011
.
PMID
15474385
.
- Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides".
Gene
.
138
(1?2): 171?4.
doi
:
10.1016/0378-1119(94)90802-8
.
PMID
8125298
.
- Hughes AE, McGibbon D, Woodward E, et al. (1996). "Localisation of a gene for chondrocalcinosis to chromosome 5p".
Hum. Mol. Genet
.
4
(7): 1225?8.
doi
:
10.1093/hmg/4.7.1225
.
PMID
8528213
.
- Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library".
Gene
.
200
(1?2): 149?56.
doi
:
10.1016/S0378-1119(97)00411-3
.
PMID
9373149
.
- Nurnberg P, Tinschert S, Mrug M, et al. (1997).
"The gene for autosomal dominant craniometaphyseal dysplasia maps to chromosome 5p and is distinct from the growth hormone-receptor gene"
.
Am. J. Hum. Genet
.
61
(4): 918?23.
doi
:
10.1086/514880
.
PMC
1716005
.
PMID
9382103
.
- Andrew LJ, Brancolini V, de la Pena LS, et al. (1999).
"Refinement of the chromosome 5p locus for familial calcium pyrophosphate dihydrate deposition disease"
.
Am. J. Hum. Genet
.
64
(1): 136?45.
doi
:
10.1086/302186
.
PMC
1377711
.
PMID
9915952
.
- Rojas K, Serrano de la Pena L, Gallardo T, et al. (2000). "Physical map and characterization of transcripts in the candidate interval for familial chondrocalcinosis at chromosome 5p15.1".
Genomics
.
62
(2): 177?83.
doi
:
10.1006/geno.1999.5997
.
PMID
10610710
.
- Nagase T, Kikuno R, Nakayama M, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro".
DNA Res
.
7
(4): 273?81.
doi
:
10.1093/dnares/7.4.271
.
PMID
10997877
.
- Nurnberg P, Thiele H, Chandler D, et al. (2001). "Heterozygous mutations in ANKH, the human ortholog of the mouse progressive ankylosis gene, result in craniometaphyseal dysplasia".
Nat. Genet
.
28
(1): 37?41.
doi
:
10.1038/88236
.
PMID
11326272
.
- Reichenberger E, Tiziani V, Watanabe S, et al. (2001).
"Autosomal dominant craniometaphyseal dysplasia is caused by mutations in the transmembrane protein ANK"
.
Am. J. Hum. Genet
.
68
(6): 1321?6.
doi
:
10.1086/320612
.
PMC
1226118
.
PMID
11326338
.
- Nelson PS, Clegg N, Arnold H, et al. (2002).
"The program of androgen-responsive genes in neoplastic prostate epithelium"
.
Proceedings of the National Academy of Sciences of the United States of America
.
99
(18): 11890?5.
doi
:
10.1073/pnas.182376299
.
PMC
129364
.
PMID
12185249
.
- Pendleton A, Johnson MD, Hughes A, et al. (2002).
"Mutations in ANKH cause chondrocalcinosis"
.
Am. J. Hum. Genet
.
71
(4): 933?40.
doi
:
10.1086/343054
.
PMC
378546
.
PMID
12297987
.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"
.
Proceedings of the National Academy of Sciences of the United States of America
.
99
(26): 16899?903.
doi
:
10.1073/pnas.242603899
.
PMC
139241
.
PMID
12477932
.
- Tsui FW, Tsui HW, Cheng EY, et al. (2003). "Novel genetic markers in the 5'-flanking region of ANKH are associated with ankylosing spondylitis".
Arthritis Rheum
.
48
(3): 791?7.
doi
:
10.1002/art.10844
.
PMID
12632434
.
- Clark HF, Gurney AL, Abaya E, et al. (2003).
"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment"
.
Genome Res
.
13
(10): 2265?70.
doi
:
10.1101/gr.1293003
.
PMC
403697
.
PMID
12975309
.
- Williams CJ, Pendleton A, Bonavita G, et al. (2003). "Mutations in the amino terminus of ANKH in two US families with calcium pyrophosphate dihydrate crystal deposition disease".
Arthritis Rheum
.
48
(9): 2627?31.
doi
:
10.1002/art.11133
.
PMID
13130483
.
????? ?? ?????
[
??????
]