CCL26

Search for
Structures	Swiss-model
Domains	InterPro

chemokine (C-C motif) ligand 26
chemokine (C-C motif) ligand 26
Identifiers
Symbol	CCL26
Alt. symbols	SCYA26, MIP-4alpha, eotaxin-3, IMAC, MIP-4a, TSC-1
NCBI gene	10344
HGNC	10625
OMIM	604697
PDB	1G2T
RefSeq	NM_006072
UniProt	Q9Y258
Other data
Locus	Chr. 7 q11.2
Structures
Search for
Structures	Swiss-model
Domains	InterPro

Chemokine (C-C motif) ligand 26 (CCL26) is a small cytokine belonging to the CC chemokine family that is also called Eotaxin-3 , Macrophage inflammatory protein 4-alpha (MIP-4-alpha), Thymic stroma chemokine-1 (TSC-1), and IMAC. It is expressed by several tissues including heart , lung and ovary , and in endothelial cells that have been stimulated with the cytokine interleukin 4 . ^[1]^[2] CCL26 is chemotactic for eosinophils and basophils and elicits its effects by binding to the cell surface chemokine receptor CCR3 . ^[3] This gene for chemokine is located on human chromosome 7 . ^[4]

References [ edit ]

^ Shinkai et al. A novel human CC chemokine, eotaxin-3, which is expressed in IL-4-stimulated vascular endothelial cells, exhibits potent activity toward eosinophils. J. Immunol. 163:1602-1610, 1999.
^ Guo et al. Molecular cloning and characterization of a novel human CC chemokine, SCYA26. Genomics 58:313-317, 1999.
^ Kitaura et al. Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3. J. Biol. Chem. 274:27975-27980, 1999.
^ Hillier et al. The DNA sequence of human chromosome 7. Nature 424:157-164, 2003.

External links [ edit ]

CCL26 human gene location in the UCSC Genome Browser .
CCL26 human gene details in the UCSC Genome Browser .

This article on a gene on human chromosome 7 is a stub . You can help Wikipedia by expanding it .

[1] Shinkai et al. A novel human CC chemokine, eotaxin-3, which is expressed in IL-4-stimulated vascular endothelial cells, exhibits potent activity toward eosinophils. J. Immunol. 163:1602-1610, 1999.

[2] Guo et al. Molecular cloning and characterization of a novel human CC chemokine, SCYA26. Genomics 58:313-317, 1999.

[3] Kitaura et al. Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3. J. Biol. Chem. 274:27975-27980, 1999.

[4] Hillier et al. The DNA sequence of human chromosome 7. Nature 424:157-164, 2003.

[1]

[2]

[3]

[4]