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Model in population genetics
In
population genetics
, the
Balding?Nichols model
is a statistical description of the
allele frequencies
in the components of a sub-divided population.
[1]
With background allele frequency
p
the allele frequencies, in sub-populations separated by
Wright's
F
ST
F
, are distributed according to independent draws from
where
B
is the
Beta distribution
. This distribution has mean
p
and variance
Fp
(1 ?
p
).
[2]
The model is due to
David Balding
and
Richard Nichols
and is widely used in the forensic analysis of
DNA profiles
and in population models for
genetic epidemiology
.
References
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edit
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Discrete
univariate
| with finite
support
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with infinite
support
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Continuous
univariate
| supported on a
bounded interval
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supported on a
semi-infinite
interval
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supported
on the whole
real line
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with support
whose type varies
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Mixed
univariate
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Multivariate
(joint)
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Directional
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Degenerate
and
singular
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Families
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