SSBP1

SSBP1
??? ??????
??? ?????? ????????	Ortholog search: PDBe RCSB
????? ???? ?????? ??? ?????? ????????
	1S3O , 2DUD , 3ULL
??????
????? ?????	SSBP1 , Mt-SSB, SOSS-B1, SSBP, mtSSB, single stranded DNA binding protein 1, OPA13
?????? ??????	??????? ???????? ??????? ??? ???????? 600439 MGI: MGI:1920040 HomoloGene: 74462 GeneCards: 6742
??? ?????? ??????
????? ??????	? ??? ?? ?? ?? ; ? single-stranded DNA binding ; ? chromatin binding ; ? ?GO:0001948? ?GO:0016582 ??? ??????? ; ? RNA binding ;
?????? ?????	? ?????? ????????????? ; ? mitochondrial nucleoid ; ? ?????? ???? ????? ; ? ??????????? ; ? ???? ; ? ?????? ;
?????? ?????	? ???? ????? ?????? ?????? ????? ???????? ; ? mitochondrion organization ; ? mitochondrion morphogenesis ; ? positive regulation of helicase activity ; ? mitochondrial DNA replication ;
	???????: Amigo / QuickGO
??? ??????? ?? ????? ?????? ????????
	?????? ?? ?????? ??????? ????????
??????? ???????
	Q04837 ; C9K0U8
	Q9CYR0
	?NM_001256510? ?NM_001256511? ?NM_001256512? ?NM_001256513? ?NM_003143? ?NR_046269? ?XM_005250048? ?XM_005250049? ?XM_005250050 XM_005250051? ?NM_001256510? ?NM_001256511? ?NM_001256512? ?NM_001256513? ?NM_003143? ?NR_046269? ?XM_005250048? ?XM_005250049? ?XM_005250050
	?NM_028358? ?NM_212468? ?XM_006506329? ?XM_017321664? ?NM_001364578 NM_001286663? ?NM_028358? ?NM_212468? ?XM_006506329? ?XM_017321664? ?NM_001364578
	?NP_001243440? ?NP_001243441? ?NP_001243442? ?NP_003134? ?XP_005250105? ?XP_005250106? ?XP_005250107? ?XP_005250108 NP_001243439? ?NP_001243440? ?NP_001243441? ?NP_001243442? ?NP_003134? ?XP_005250105? ?XP_005250106? ?XP_005250107? ?XP_005250108
	?NP_082634? ?NP_997633? ?XP_006506392? ?XP_017177153? ?NP_001351507 NP_001273592? ?NP_082634? ?NP_997633? ?XP_006506392? ?XP_017177153? ?NP_001351507
	???? ??????
????/???? ?????	????/???? ???

SSBP1 ? ( Single stranded DNA binding protein 1 ) ??? ?????? ?????? ?????? ??? SSBP1 ?? ??????? . ^[1]^[2]

??????? [ ??? ]

??????? ???????? [ ??? ]

??????? [ ??? ]

^ "Entrez Gene: SSBP1 single-stranded DNA binding protein 1" . ????? ?? ????? ?? 2010-12-05.
^ Tiranti V? Rossi E? Ruiz-Carrillo A? Rossi G? Rocchi M? DiDonato S? Zuffardi O? Zeviani M (????? 1995). "Chromosomal localization of mitochondrial transcription factor A (TCF6), single-stranded DNA-binding protein (SSBP), and endonuclease G (ENDOG), three human housekeeping genes involved in mitochondrial biogenesis". Genomics . ?. 25 ?. 2: 559?64. DOI : 10.1016/0888-7543(95)80058-T . PMID : 7789991 .

????? ?????? [ ??? ]

Tiranti V? Rocchi M? DiDonato S? Zeviani M (????? 1993). "Cloning of human and rat cDNAs encoding the mitochondrial single-stranded DNA-binding protein (SSB)". Gene . ?. 126 ?. 2: 219?25. DOI : 10.1016/0378-1119(93)90370-I . PMID : 8482537 .
Yang C? Curth U? Urbanke C? Kang C (?????? 1997). "Crystal structure of human mitochondrial single-stranded DNA binding protein at 2.4 A resolution". Nature Structural Biology . ?. 4 ?. 2: 153?7. DOI : 10.1038/nsb0297-153 . PMID : 9033597 .
Schultz RA? Swoap SJ? McDaniel LD? Zhang B? Koon EC? Garry DJ? Li K? Williams RS (?????? 1998). "Differential expression of mitochondrial DNA replication factors in mammalian tissues". The Journal of Biological Chemistry . ?. 273 ?. 6: 3447?51. DOI : 10.1074/jbc.273.6.3447 . PMID : 9452467 . {{ ??????? ?????? ????? }}: ????? ?????????: ??? ????? ??? ???? ( link )
Spelbrink JN? Toivonen JM? Hakkaart GA? Kurkela JM? Cooper HM? Lehtinen SK? Lecrenier N? Back JW? Speijer D? Foury F? Jacobs HT (????? 2000). "In vivo functional analysis of the human mitochondrial DNA polymerase POLG expressed in cultured human cells". The Journal of Biological Chemistry . ?. 275 ?. 32: 24818?28. DOI : 10.1074/jbc.M000559200 . PMID : 10827171 . {{ ??????? ?????? ????? }}: ????? ?????????: ??? ????? ??? ???? ( link )
Muller-Hocker J? Schafer S? Li K (?????? 2001). "Immunocytochemical localization of mitochondrial single-stranded DNA-binding protein in mitochondria-rich cells of normal and neoplastic human tissue". Applied Immunohistochemistry & Molecular Morphology . ?. 9 ?. 3: 276?80. DOI : 10.1097/00022744-200109000-00013 . PMID : 11556757 .
Takamatsu C? Umeda S? Ohsato T? Ohno T? Abe Y? Fukuoh A? Shinagawa H? Hamasaki N? Kang D (???? 2002). "Regulation of mitochondrial D-loops by transcription factor A and single-stranded DNA-binding protein" . EMBO Reports . ?. 3 ?. 5: 451?6. DOI : 10.1093/embo-reports/kvf099 . PMC : 1084112 . PMID : 11964388 .
Chen L? Segal D? Hukriede NA? Podtelejnikov AV? Bayarsaihan D? Kennison JA? Ogryzko VV? Dawid IB? Westphal H (?????? 2002). "Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development" . Proceedings of the National Academy of Sciences of the United States of America . ?. 99 ?. 22: 14320?5. DOI : 10.1073/pnas.212532399 . PMC : 137882 . PMID : 12381786 .
Diez-Tascon C? Dodds KG? Crawford AM (?????? 2002). "Linkage mapping of the ovine single-stranded DNA-binding protein 1 (SSBP1) using microsatellite marker OARCDT7" . Animal Genetics . ?. 33 ?. 6: 468. DOI : 10.1046/j.1365-2052.2002.00938_1.x . PMID : 12464025 .
Bayarsaihan D (?????? 2002). "SSDP1 gene encodes a protein with a conserved N-terminal FORWARD domain". Biochimica et Biophysica Acta . ?. 1599 ?. 1?2: 152?5. DOI : 10.1016/s1570-9639(02)00376-x . PMID : 12479417 .
Pocernich CB? Poon HF? Boyd-Kimball D? Lynn BC? Nath A? Klein JB? Butterfield DA (?????? 2005). "Proteomic analysis of oxidatively modified proteins induced by the mitochondrial toxin 3-nitropropionic acid in human astrocytes expressing the HIV protein tat". Brain Research. Molecular Brain Research . ?. 133 ?. 2: 299?306. DOI : 10.1016/j.molbrainres.2004.10.024 . PMID : 15710247 .

??? ???? ????? ?? ??? ??? ???????? 7 ????? ???????. ????? ???? ?? ???????.

[entrez-1] "Entrez Gene: SSBP1 single-stranded DNA binding protein 1" . ????? ?? ????? ?? 2010-12-05.

[pmid7789991-2] Tiranti V? Rossi E? Ruiz-Carrillo A? Rossi G? Rocchi M? DiDonato S? Zuffardi O? Zeviani M (????? 1995). "Chromosomal localization of mitochondrial transcription factor A (TCF6), single-stranded DNA-binding protein (SSBP), and endonuclease G (ENDOG), three human housekeeping genes involved in mitochondrial biogenesis". Genomics . ?. 25 ?. 2: 559?64. DOI : 10.1016/0888-7543(95)80058-T . PMID : 7789991 .

[1]

[2]

????????? ??????	???? ??????? ???????? ??? ????? (OMIM) : 600439
???????? ????????	Ensembl Transcript ID : ENST00000496622 ???? ????? ?????? ??????? (UMLS CUI) : C1420424