PCOLCE2

PCOLCE2
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????? ?????	PCOLCE2 , PCPE2, procollagen C-endopeptidase enhancer 2
?????? ??????	??????? ???????? ??????? ??? ???????? 607064 MGI: MGI:1923727 HomoloGene: 8357 GeneCards: 26577
??? ?????? ??????
????? ??????	? heparin binding ; ? peptidase activator activity ; ? collagen binding ;
?????? ?????	? ?????? ???? ?????? ;
?????? ?????	? positive regulation of peptidase activity ; ? cellular response to leukemia inhibitory factor ;
	???????: Amigo / QuickGO
??? ??????? ?? ????? ?????? ????????
	?????? ?? ?????? ??????? ????????
??????? ???????
	Q9UKZ9
	Q8R4W6
	NM_013363
	NM_029620
	NP_037495
	NP_083896
	???? ??????
????/???? ?????	????/???? ???

PCOLCE2 ? ( Procollagen C-endopeptidase enhancer 2 ) ??? ?????? ?????? ?????? ??? PCOLCE2 ?? ??????? . ^[1]^[2]

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^ "Entrez Gene: PCOLCE2 procollagen C-endopeptidase enhancer 2" . ????? ?? ????? ?? 2010-12-05.
^ Xu H? Acott TS? Wirtz MK (?????? 2000). "Identification and expression of a novel type I procollagen C-proteinase enhancer protein gene from the glaucoma candidate region on 3q21-q24". Genomics . ?. 66 ?. 3: 264?73. DOI : 10.1006/geno.2000.6229 . PMID : 10873381 .

????? ?????? [ ??? ]

Maruyama K? Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene . ?. 138 ?. 1?2: 171?4. DOI : 10.1016/0378-1119(94)90802-8 . PMID : 8125298 .
Suzuki Y? Yoshitomo-Nakagawa K? Maruyama K? ?????? (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene . ?. 200 ?. 1?2: 149?56. DOI : 10.1016/S0378-1119(97)00411-3 . PMID : 9373149 .
Kumar S? Connor JR? Dodds RA? ?????? (2001). "Identification and initial characterization of 5000 expressed sequenced tags (ESTs) each from adult human normal and osteoarthritic cartilage cDNA libraries". Osteoarthr. Cartil . ?. 9 ?. 7: 641?53. DOI : 10.1053/joca.2001.0421 . PMID : 11597177 .
Steiglitz BM? Greenspan DS (2002). "Assignment of the mouse Pcolce2 gene, which encodes procollagen C-proteinase enhancer protein 2, to chromosome 9 and localization of PCOLCE2 to human chromosome 3q23". Cytogenet. Cell Genet . ?. 95 ?. 3?4: 244?5. DOI : 10.1159/000059356 . PMID : 12063410 .
Steiglitz BM? Keene DR? Greenspan DS (2003). "PCOLCE2 encodes a functional procollagen C-proteinase enhancer (PCPE2) that is a collagen-binding protein differing in distribution of expression and post-translational modification from the previously described PCPE1". J. Biol. Chem . ?. 277 ?. 51: 49820?30. DOI : 10.1074/jbc.M209891200 . PMID : 12393877 . {{ ??????? ?????? ????? }}: ????? ?????????: ??? ????? ??? ???? ( link )
Strausberg RL? Feingold EA? Grouse LH? ?????? (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . ?. 99 ?. 26: 16899?903. DOI : 10.1073/pnas.242603899 . PMC : 139241 . PMID : 12477932 .
Clark HF? Gurney AL? Abaya E? ?????? (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment" . Genome Res . ?. 13 ?. 10: 2265?70. DOI : 10.1101/gr.1293003 . PMC : 403697 . PMID : 12975309 .
Zhang Z? Henzel WJ (2005). "Signal peptide prediction based on analysis of experimentally verified cleavage sites" . Protein Sci . ?. 13 ?. 10: 2819?24. DOI : 10.1110/ps.04682504 . PMC : 2286551 . PMID : 15340161 .
Gerhard DS? Wagner L? Feingold EA? ?????? (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . ?. 14 ?. 10B: 2121?7. DOI : 10.1101/gr.2596504 . PMC : 528928 . PMID : 15489334 .
Otsuki T? Ota T? Nishikawa T? ?????? (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res . ?. 12 ?. 2: 117?26. DOI : 10.1093/dnares/12.2.117 . PMID : 16303743 .

??? ???? ????? ?? ??? ??? ???????? 3 ????? ???????. ????? ???? ?? ???????.

[entrez-1] "Entrez Gene: PCOLCE2 procollagen C-endopeptidase enhancer 2" . ????? ?? ????? ?? 2010-12-05.

[pmid10873381-2] Xu H? Acott TS? Wirtz MK (?????? 2000). "Identification and expression of a novel type I procollagen C-proteinase enhancer protein gene from the glaucoma candidate region on 3q21-q24". Genomics . ?. 66 ?. 3: 264?73. DOI : 10.1006/geno.2000.6229 . PMID : 10873381 .

[1]

[2]

????????? ??????	???? ??????? ???????? ??? ????? (OMIM) : 607064
???????? ????????	Ensembl Transcript ID : ENST00000648195 ???? ????? ?????? ??????? (UMLS CUI) : C1418384