GNG11

GNG11
??????
????? ?????	GNG11 , GNGT11, G protein subunit gamma 11, HG3H1
?????? ??????	??????? ???????? ??????? ??? ???????? 604390 MGI: MGI:1913316 HomoloGene: 3045 GeneCards: 2791
??? ?????? ??????
????? ??????	? signal transducer activity ; ? ?GO:0006184 GTPase activity ; ? ?GO:0001948? ?GO:0016582 ??? ??????? ; ? G-protein beta-subunit binding ;
?????? ?????	? ???? ???? ; ? ???? ; ? heterotrimeric G-protein complex ; ? G-protein beta/gamma-subunit complex ;
?????? ?????	? G protein-coupled receptor signaling pathway ; ? ?GO:0072468 ????? ??????? ;
	???????: Amigo / QuickGO
??? ??????? ?? ????? ?????? ????????
	?????? ?? ?????? ??????? ????????
??????? ???????
	P61952
	P61953
	NM_004126
	NM_025331
	NP_004117
	NP_079607
	???? ??????
????/???? ?????	????/???? ???

GNG11 ? ( G protein subunit gamma 11 ) ??? ?????? ?????? ?????? ??? GNG11 ?? ??????? . ^[1]^[2]

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^ Ray K? Kunsch C? Bonner LM? Robishaw JD (?????? 1995). "Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits". J Biol Chem . ?. 270 ?. 37: 21765?71. DOI : 10.1074/jbc.270.37.21765 . PMID : 7665596 . {{ ??????? ?????? ????? }}: ????? ?????????: ??? ????? ??? ???? ( link )
^ "Entrez Gene: GNG11 guanine nucleotide binding protein (G protein), gamma 11" . ????? ?? ????? ?? 2010-12-05.

????? ?????? [ ??? ]

Downes GB? Gautam N (2000). "The G protein subunit gene families". Genomics . ?. 62 ?. 3: 544?52. DOI : 10.1006/geno.1999.5992 . PMID : 10644457 .
"Toward a complete human genome sequence". Genome Res . ?. 8 ?. 11: 1097?108. 1999. DOI : 10.1101/gr.8.11.1097 . PMID : 9847074 .
Strausberg RL? Feingold EA? Grouse LH? ?????? (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . ?. 99 ?. 26: 16899?903. DOI : 10.1073/pnas.242603899 . PMC : 139241 . PMID : 12477932 .
Cuello F? Schulze RA? Heemeyer F? ?????? (2003). "Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta". J. Biol. Chem . ?. 278 ?. 9: 7220?6. DOI : 10.1074/jbc.M210304200 . PMID : 12486123 . {{ ??????? ?????? ????? }}: ????? ?????????: ??? ????? ??? ???? ( link )
Scherer SW? Cheung J? MacDonald JR? ?????? (2003). "Human chromosome 7: DNA sequence and biology" . Science . ?. 300 ?. 5620: 767?72. DOI : 10.1126/science.1083423 . PMC : 2882961 . PMID : 12690205 .
Hillier LW? Fulton RS? Fulton LA? ?????? (2003). "The DNA sequence of human chromosome 7". Nature . ?. 424 ?. 6945: 157?64. DOI : 10.1038/nature01782 . PMID : 12853948 .
Gerhard DS? Wagner L? Feingold EA? ?????? (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . ?. 14 ?. 10B: 2121?7. DOI : 10.1101/gr.2596504 . PMC : 528928 . PMID : 15489334 .
Barrios-Rodiles M? Brown KR? Ozdamar B? ?????? (2005). "High-throughput mapping of a dynamic signaling network in mammalian cells". Science . ?. 307 ?. 5715: 1621?5. DOI : 10.1126/science.1105776 . PMID : 15761153 .
Ruiz-Ballesteros E? Mollejo M? Rodriguez A? ?????? (2005). "Splenic marginal zone lymphoma: proposal of new diagnostic and prognostic markers identified after tissue and cDNA microarray analysis". Blood . ?. 106 ?. 5: 1831?8. DOI : 10.1182/blood-2004-10-3898 . PMID : 15914563 .
Rual JF? Venkatesan K? Hao T? ?????? (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . ?. 437 ?. 7062: 1173?8. DOI : 10.1038/nature04209 . PMID : 16189514 .
Hossain MN? Sakemura R? Fujii M? Ayusawa D (2007). "G-protein gamma subunit GNG11 strongly regulates cellular senescence". Biochem. Biophys. Res. Commun . ?. 351 ?. 3: 645?50. DOI : 10.1016/j.bbrc.2006.10.112 . PMID : 17092487 .

??? ???? ????? ?? ??? ??? ???????? 7 ????? ???????. ????? ???? ?? ???????.

[1] Ray K? Kunsch C? Bonner LM? Robishaw JD (?????? 1995). "Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits". J Biol Chem . ?. 270 ?. 37: 21765?71. DOI : 10.1074/jbc.270.37.21765 . PMID : 7665596 . {{ ??????? ?????? ????? }}: ????? ?????????: ??? ????? ??? ???? ( link )

[2] "Entrez Gene: GNG11 guanine nucleotide binding protein (G protein), gamma 11" . ????? ?? ????? ?? 2010-12-05.

[1]

[2]

????????? ??????	???? ??????? ???????? ??? ????? (OMIM) : 604390
???????? ????????	Ensembl Transcript ID : ENST00000248564 ???? ????? ?????? ??????? (UMLS CUI) : C1415154