ASB3

ASB3
??????
????? ?????	ASB3 , ASB-3, ankyrin repeat and SOCS box containing 3
?????? ??????	??????? ???????? ??????? ??? ???????? 605760 MGI: MGI:1929749 HomoloGene: 9391 GeneCards: 51130
??? ?????? ??????
????? ??????	? ?GO:0001948? ?GO:0016582 ??? ??????? ; ? ubiquitin protein ligase binding ; ? ?GO:0050372 ubiquitin-protein transferase activity ;
?????? ?????	? ????????? ; ? ???? ; ? ubiquitin ligase complex ; ? ????? ????? ;
?????? ?????	? protein ubiquitination ; ? ?GO:0007243 intracellular signal transduction ; ? ????? ?? ??? ??????? ;
	???????: Amigo / QuickGO
??????? ???????
	Q9Y575
	Q9WV72
	?NM_001201965? ?NM_016115 NM_145863? ?NM_001201965? ?NM_016115
	?XM_006514771? ?XM_036156890 NM_023906? ?XM_006514771? ?XM_036156890
	NP_001157637
	?XP_006514834? ?XP_036012783 NP_076395? ?XP_006514834? ?XP_036012783
	???? ??????
????/???? ?????	????/???? ???

ASB3 ? ( Ankyrin repeat and SOCS box containing 3 ) ??? ?????? ?????? ?????? ??? ASB3 ?? ??????? . ^[1]^[2]

??????? [ ??? ]

??????? ???????? [ ??? ]

??????? [ ??? ]

^ Chung AS? Guan YJ? Yuan ZL? Albina JE? Chin YE (???? 2005). "Ankyrin repeat and SOCS box 3 (ASB3) mediates ubiquitination and degradation of tumor necrosis factor receptor II" . Mol Cell Biol . ?. 25 ?. 11: 4716?26. DOI : 10.1128/MCB.25.11.4716-4726.2005 . PMC : 1140645 . PMID : 15899873 .
^ "Entrez Gene: ASB3 ankyrin repeat and SOCS box-containing 3" . ????? ?? ????? ?? 2010-12-05.

????? ?????? [ ??? ]

Kile BT? Schulman BA? Alexander WS? ?????? (2002). "The SOCS box: a tale of destruction and degradation". Trends Biochem. Sci . ?. 27 ?. 5: 235?41. DOI : 10.1016/S0968-0004(02)02085-6 . PMID : 12076535 .
Maruyama K? Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene . ?. 138 ?. 1?2: 171?4. DOI : 10.1016/0378-1119(94)90802-8 . PMID : 8125298 .
Suzuki Y? Yoshitomo-Nakagawa K? Maruyama K? ?????? (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene . ?. 200 ?. 1?2: 149?56. DOI : 10.1016/S0378-1119(97)00411-3 . PMID : 9373149 .
Kile BT? Viney EM? Willson TA? ?????? (2001). "Cloning and characterization of the genes encoding the ankyrin repeat and SOCS box-containing proteins Asb-1, Asb-2, Asb-3 and Asb-4". Gene . ?. 258 ?. 1?2: 31?41. DOI : 10.1016/S0378-1119(00)00402-9 . PMID : 11111040 .
Kile BT? Metcalf D? Mifsud S? ?????? (2001). "Functional analysis of Asb-1 using genetic modification in mice" . Mol. Cell. Biol . ?. 21 ?. 18: 6189?97. DOI : 10.1128/MCB.21.18.6189-6197.2001 . PMC : 87336 . PMID : 11509662 .
Strausberg RL? Feingold EA? Grouse LH? ?????? (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . ?. 99 ?. 26: 16899?903. DOI : 10.1073/pnas.242603899 . PMC : 139241 . PMID : 12477932 .
Ota T? Suzuki Y? Nishikawa T? ?????? (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet . ?. 36 ?. 1: 40?5. DOI : 10.1038/ng1285 . PMID : 14702039 .
Gerhard DS? Wagner L? Feingold EA? ?????? (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . ?. 14 ?. 10B: 2121?7. DOI : 10.1101/gr.2596504 . PMC : 528928 . PMID : 15489334 .
Ewing RM? Chu P? Elisma F? ?????? (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . ?. 3 ?. 1: 89. DOI : 10.1038/msb4100134 . PMC : 1847948 . PMID : 17353931 .

??? ???? ????? ?? ??? ??? ???????? 2 ????? ???????. ????? ???? ?? ???????.

[1] Chung AS? Guan YJ? Yuan ZL? Albina JE? Chin YE (???? 2005). "Ankyrin repeat and SOCS box 3 (ASB3) mediates ubiquitination and degradation of tumor necrosis factor receptor II" . Mol Cell Biol . ?. 25 ?. 11: 4716?26. DOI : 10.1128/MCB.25.11.4716-4726.2005 . PMC : 1140645 . PMID : 15899873 .

[2] "Entrez Gene: ASB3 ankyrin repeat and SOCS box-containing 3" . ????? ?? ????? ?? 2010-12-05.

[1]

[2]

????????? ??????	???? ??????? ???????? ??? ????? (OMIM) : 605760
???????? ????????	Ensembl Transcript ID : ENST00000498475 ???? ????? ?????? ??????? (UMLS CUI) : C1423909