ARFIP1

ARFIP1
??????
????? ?????	ARFIP1 , HSU52521, ADP ribosylation factor interacting protein 1
?????? ??????	??????? ???????? ??????? ??? ???????? 605928 MGI: MGI:1277120 HomoloGene: 8692 GeneCards: 27236
??? ?????? ??????
????? ??????	? protein domain specific binding ; ? phosphatidylinositol-4-phosphate binding ; ? phospholipid binding ;
?????? ?????	? ????? ????? ; ? trans-Golgi network membrane ; ? Golgi membrane ; ? ????????? ;
?????? ?????	? intracellular protein transport ; ? regulation of Arp2/3 complex-mediated actin nucleation ; ? regulation of protein secretion ;
	???????: Amigo / QuickGO
??? ??????? ?? ????? ?????? ????????
	; ;
	?????? ?? ?????? ??????? ????????
??????? ???????
	P53367
	G5E8V9
	?NM_001025595? ?NM_001287431? ?NM_001287432? ?NM_001287433? ?NM_014447 NM_001025593? ?NM_001025595? ?NM_001287431? ?NM_001287432? ?NM_001287433? ?NM_014447
	?NM_001293801? ?XM_006502482? ?XM_006502484? ?XM_036163483 NM_001081093? ?NM_001293801? ?XM_006502482? ?XM_006502484? ?XM_036163483
	?NP_001020766? ?NP_001274360? ?NP_001274361? ?NP_001274362? ?NP_055262? ?XP_011530170? ?XP_011530171? ?XP_011530172? ?XP_011530173? ?XP_011530174? ?XP_024309753 NP_001020764? ?NP_001020766? ?NP_001274360? ?NP_001274361? ?NP_001274362? ?NP_055262? ?XP_011530170? ?XP_011530171? ?XP_011530172? ?XP_011530173? ?XP_011530174? ?XP_024309753
	?NP_001280730? ?XP_006502545? ?XP_006502547? ?XP_036019376 NP_001074562? ?NP_001280730? ?XP_006502545? ?XP_006502547? ?XP_036019376
	???? ??????
????/???? ?????	????/???? ???

ARFIP1 ? ( ADP ribosylation factor interacting protein 1 ) ??? ?????? ?????? ?????? ??? ARFIP1 ?? ??????? . ^[1]^[2]^[3]

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^ Kanoh H? Williger BT? Exton JH (????? 1997). "Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes". J Biol Chem . ?. 272 ?. 9: 5421?9. DOI : 10.1074/jbc.272.9.5421 . PMID : 9038142 . {{ ??????? ?????? ????? }}: ????? ?????????: ??? ????? ??? ???? ( link )
^ Williger BT? Provost JJ? Ho WT? Milstine J? Exton JH (????? 1999). "Arfaptin 1 forms a complex with ADP-ribosylation factor and inhibits phospholipase D". FEBS Lett . ?. 454 ?. 1?2: 85?9. DOI : 10.1016/S0014-5793(99)00771-1 . PMID : 10413101 .
^ "Entrez Gene: ARFIP1 ADP-ribosylation factor interacting protein 1 (arfaptin 1)" . ????? ?? ????? ?? 2010-12-05.

????? ?????? [ ??? ]

Tsai SC? Adamik R? Hong JX? ?????? (1998). "Effects of arfaptin 1 on guanine nucleotide-dependent activation of phospholipase D and cholera toxin by ADP-ribosylation factor". J. Biol. Chem . ?. 273 ?. 33: 20697?701. DOI : 10.1074/jbc.273.33.20697 . PMID : 9694811 . {{ ??????? ?????? ????? }}: ????? ?????????: ??? ????? ??? ???? ( link )
Suzuki Y? Tsunoda T? Sese J? ?????? (2001). "Identification and characterization of the potential promoter regions of 1031 kinds of human genes" . Genome Res . ?. 11 ?. 5: 677?84. DOI : 10.1101/gr.gr-1640r . PMC : 311086 . PMID : 11337467 .
Strausberg RL? Feingold EA? Grouse LH? ?????? (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . ?. 99 ?. 26: 16899?903. DOI : 10.1073/pnas.242603899 . PMC : 139241 . PMID : 12477932 .
Ho WT? Exton JH? Williger BT (2003). "Arfaptin 1 inhibits ADP-ribosylation factor-dependent matrix metalloproteinase-9 secretion induced by phorbol ester in HT 1080 fibrosarcoma cells". FEBS Lett . ?. 537 ?. 1?3: 91?5. DOI : 10.1016/S0014-5793(03)00098-X . PMID : 12606037 .
Ota T? Suzuki Y? Nishikawa T? ?????? (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet . ?. 36 ?. 1: 40?5. DOI : 10.1038/ng1285 . PMID : 14702039 .
Brandenberger R? Wei H? Zhang S? ?????? (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol . ?. 22 ?. 6: 707?16. DOI : 10.1038/nbt971 . PMID : 15146197 .
Gerhard DS? Wagner L? Feingold EA? ?????? (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . ?. 14 ?. 10B: 2121?7. DOI : 10.1101/gr.2596504 . PMC : 528928 . PMID : 15489334 .
Foster LJ? Rudich A? Talior I? ?????? (2006). "Insulin-dependent interactions of proteins with GLUT4 revealed through stable isotope labeling by amino acids in cell culture (SILAC)". J. Proteome Res . ?. 5 ?. 1: 64?75. DOI : 10.1021/pr0502626 . PMID : 16396496 .

??? ???? ????? ?? ??? ??? ???????? 4 ????? ???????. ????? ???? ?? ???????.

[pmid9038142-1] Kanoh H? Williger BT? Exton JH (????? 1997). "Arfaptin 1, a putative cytosolic target protein of ADP-ribosylation factor, is recruited to Golgi membranes". J Biol Chem . ?. 272 ?. 9: 5421?9. DOI : 10.1074/jbc.272.9.5421 . PMID : 9038142 . {{ ??????? ?????? ????? }}: ????? ?????????: ??? ????? ??? ???? ( link )

[pmid10413101-2] Williger BT? Provost JJ? Ho WT? Milstine J? Exton JH (????? 1999). "Arfaptin 1 forms a complex with ADP-ribosylation factor and inhibits phospholipase D". FEBS Lett . ?. 454 ?. 1?2: 85?9. DOI : 10.1016/S0014-5793(99)00771-1 . PMID : 10413101 .

[entrez-3] "Entrez Gene: ARFIP1 ADP-ribosylation factor interacting protein 1 (arfaptin 1)" . ????? ?? ????? ?? 2010-12-05.

[1]

[2]

[3]

????????? ??????	???? ??????? ???????? ??? ????? (OMIM) : 605928
???????? ????????	Ensembl Transcript ID : ENST00000514499 ???? ????? ?????? ??????? (UMLS CUI) : C1427585