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CAS	104-76-7
??? ???	CID 7720
ECHA InfoCard ID	100.002.941
??? ??????	7434
?????? ??????	XZV7TAA77P
?????	C02498
ChEBI	CHEBI:16011
ChEMBL	CHEMBL31637
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?????? ??????????	C 8 H 18 O
?????? ????????	833 ???? ??? ???
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???? ????????	-76 °C (-105 °F)
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????? ????? ??????? ?? ???? ?????? ????? ??? ?????? ???? ?????? ??? ????? ?? ???? ???? ????? ???? ??????? ?? ?????? ????? ???? ??????? ???? ??? ?? ???? ???????? ??????? . ??? ????? ???? ????? ??????? ??????? ???????? ??? ???? ???? (????? ???? ?? 2?000?000?000 ???????? ???????) ???? ???????? ?? ?????? ?? ????????? ??? ????? ????????? ????????? ? ??????? ? ??? ??????? ????? ?????? ?? ????? ???? ???????? ???? ??? ???????? ? ????????? . ^[1] ????? ????? ??????? ??????? ?? ???????? ? ???????? ? ??????? . ^[2]^[3] ?????? ????? ???? ????? ??????? ??????? ?????? ?????? ????? ??? ???? ????? ?????? ?? ???? ??????? ??????? R ?"?????? ?????? ??? ???? ???? ????? ??? ???? ?????? ??????? S. ^[4]^[5]

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????? ??? ???? 2-????? ??????? ???????? ???? ???? ?? ???????? ????????? ???????? (????????????) ????????? ???? ????? ????????????? ??? ??? ???????? ??????? ?????? ???????? ?????? ?????????? ??????? ????? ??? ?? ?????? ?? ????? ??? ????? ??? ????? ??? ?? ?????? ?????????? ?? 6-????? ??????? 1-??. ^[6] ????? ???? ?????????? ?????????? ????? ?????? ???????????? ??? ??? 6-????? ??????? 1-??.

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????? ???? ???? ??????? ?? ???? ????? ??????? ??????? ??? ??? ??????? . ????? ?????? ?????? ????? ??????? ??????? ???? ?????? ??????? ?????? ??? ???????? ??????? ???? ????? ?????? ????? ??? ????? ??????? ??????? ????? ?? ???? ???? .

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?????? ????? ??????? ??????? ???? ???? ????? ????? ???????? ????? ???????? ????? ????? ????? ???????? ??? ??????? ?? ??? ???????? ? ??? ?????? ?? ??????? ?? ???????????????? ?????????? ???????? ?????? ???? ?????????? ?????? ???? ?????? ????? ??????? ?????? ?? ????? ??????? ?????? ??????? ??????? ??????? ?????? . ???? ???????? ?? ????? ????? ?????? ?????? ???????? ????? ?????? . ^[7]

?????? ?????? ????? ??????? ??????? ?????? ???? ????????? ????????? ??? ?? ????? ???????? ????? ??????? ? ??? ????? ?????? ??? ????? ??????? ???? ???? ?????? .

???? ??????? ???? ?????? ????? ????? ????? ??????? ?? ????? ????? ?????? ????? ?????? ?? ???????? ????? ???????? ?????? ???? ????? ??????? ???? (????? ????? ?????) ???????? ??????? ???? ?????????? ???? ?????? ?? ???? ????? ????? ?????? ?? ????? ????? ??????? ??? ??? ????? ??????????.

??????? ???????? [ ??? ]

??? ????? ????? ??????? ??????? ??????? ?? ???? ??????? ???????? ??????? ?????? ??????? ? ??? ????? ?????????? ?????? ??????. ?????? ??? 2500000 ????? ?? ????? ????? ????????? ??????? ???????? ??? ???????. ^[8]^[9]

????? ?????? ??? ?????? ?????? ??????? (?-????????) ?? ???? ????? ????? ?????????? ???? ???? ?????? ?? ????? ???? ?? ?????? ???????. ????? ???? ??? ????????? ?????? ?-????????? ????????????? ??? ???? ???? ????? ??????? ???????. ???? ??????? ??? ????????? ???????? ???????? ??? ??????? ???? ?????? ?????. ???? ??? ??????? ??? ?? ???? ????? ????? ?????? ????? ???? ?????? ?? ?????? ?????. ^[10]

?????? ??? ????? ?????? ??????? ???????? [ ??? ]

???? ???? 2-????? ????????? ????? ?????? ?? ??????? ?????????? ??????? ?????? ??????? ??? ?? ??? 2-3 ????/???????? ?? ???????. ??? ???? ?? ?????? 2-????? ????????? ??????? ????????? ?????? ?? ??? ???????? ?????? ???? ????? ????? ?????? ???????? ? ??? ???? ?????? ???????. ????? 2-????? ??????? ?? ?????? ?? ???? ?????? ?????? ????? ?????? ??????? ??? ???????? ???? ?? ?????? ???? ????. ^[11]^[12]

???? ????? ?? ???? ????? ????? ??? ???? 2-????? ????????? ?????? ???? ?????? ?????? ?????? ?? ??????? ?? ?? ????? ?????? ?????. ??????? ?? ??? ???? ?? ????? ??????? ??????? ????? 2-????? ?????????? ????? ?????? ?????? ??? ??? 2-????? ?????????? ?? ???? ????? ?????? ????????. ^[13]^[14] ??? ??? ?? ??? 2-????? ?????????? ??????? ???????? ??? ??? ?????????? ???? ????? ?? ???? ???????? ??????? . ^[15]^[16]^[17]^[18]^[19]

??????? [ ??? ]

^ Helmut Bahrmann? Heinz-Dieter Hahn? Dieter Mayer (2005). "2-Ethylhexanol". Ullmann's Encyclopedia of Industrial Chemistry . Weinheim: Wiley-VCH. DOI : 10.1002/14356007.a10_137 . ISBN : 978-3527306732 .
^ Fan? Wenlai? Qian? Michael C. (2006). "Characterization of Aroma Compounds of Chinese "Wuliangye" and "Jiannanchun" Liquors by Aroma Extract Dilution Analysis". Journal of Agricultural and Food Chemistry . ?. 54 ?. 7: 2695?2704. DOI : 10.1021/jf052635t . PMID : 16569063 .
^ Mayuoni-Kirshinbaum? Lina? Tietel? Zipora? Porat? Ron? Ulrich? Detlef (2012). "Identification of aroma-active compounds in 'wonderful' pomegranate fruit using solvent-assisted flavour evaporation and headspace solid-phase micro-extraction methods". European Food Research and Technology . ?. 235 ?. 2: 277?283. DOI : 10.1007/s00217-012-1757-0 . S2CID : 97102092 .
^ Klaus Rettinger? Christian Burschka? Peter Scheeben? Heike Fuchs? Armin Mosandl (1991). "Chiral 2-alkylbranched acids, esters and alcohols. Preparation and stereospecific flavour evaluation" (PDF) . Tetrahedron: Asymmetry . ?. 2 ?. 10: 965?968. DOI : 10.1016/S0957-4166(00)86137-6 . ????? ?? ????? (PDF) ?? 2021-11-04.
^ McGinty? D.? Scognamiglio? J.? Letizia? C.S.? Api? A.M. (2010). "Fragrance material review on 2-ethyl-1-hexanol". Food and Chemical Toxicology . ?. 48: S115?S129. DOI : 10.1016/j.fct.2010.05.042 . PMID : 20659633 .
^ "Rule A-2. Saturated Branched-chain Compounds and Univalent Radicals (ACYCLIC HYDROCARBONS)" . www.acdlabs.com . ????? ?? ????? ?? 2021-08-30.
^ "Product Spotlight: 2-Ethylhexanol" . 12 ?????? 2019. ????? ?? ????? ?? 2021-04-14.
^ C. Kohlpaintner? M. Schulte? J. Falbe? P. Lappe? J. Weber (2008). "Aldehydes, Aliphatic". Ullmann's Encyclopedia of Industrial Chemistry . Weinheim: Wiley-VCH. DOI : 10.1002/14356007.a01_321.pub2 . ISBN : 978-3527306732 .
^ Ashford’s Dictionary of Industrial Chemicals, Third edition, 2011, page 4180-4181.
^ Miller? Robert? Bennett? George (????? 1961). "Producing 2-Ethylhexanol by the Guerbet Reaction". Industrial & Engineering Chemistry . ?. 53 ?. 1: 33?36. DOI : 10.1021/ie50613a027 .
^ Ernstgard? L.? Norback? D. (2010). "Acute effects of exposure to 1 mg/m(3) of vaporized 2-ethyl-1-hexanol in humans". Indoor Air . ?. 20 ?. 2: 168?75. DOI : 10.1111/j.1600-0668.2009.00638.x . PMID : 20409194 .
^ Hildenbrand? S.? Wodarz? R. (2009). "Biomonitoring of the di(2-ethylhexyl) phthalate metabolites mono(2-ethyl-5-hydroxyhexyl) phthalate and mono(2-ethyl-5-oxohexyl) phthalate in children and adults during the course of time and seasons". International Journal of Hygiene and Environmental Health . ?. 212 ?. 6: 679?84. DOI : 10.1016/j.ijheh.2009.06.003 . PMID : 19615938 .
^ Deisinger, PJ, Boatman, RJ, Guest, D (15 Mar 2009). "Metabolism of 2-ethylhexanol administered orally and dermally to the female Fischer-344 rat" . hero.epa.gov (???????????). Archived from the original on 2021-11-22 . Retrieved 2021-04-09 . {{ ??????? ??? }}: ????? ?????????: ????? ??????: ????? ???????? ( link )
^ Eastman Kodak Company, Eastman Kodak (15 Mar 2009). "Pharmacokinetic studies with 2-ethylhexanol in the female fischer 344 rat (final report) with attachments and cover letter dated 050791" . hero.epa.gov (???????????). Archived from the original on 2021-11-22 . Retrieved 2021-04-09 .
^ Pennanen? Sirpa? Tuovinen? Kai? Huuskonen? Hannele? Komulainen? Hannu (1992). "The developmental toxicity of 2-ethylhexanoic acid in Wistar rats" . Fundamental and Applied Toxicology . ?. 19 ?. 4: 505?511. DOI : 10.1016/0272-0590(92)90088-Y . PMID : 1426708 . ????? ?? ????? ?? 2021-11-22. {{ ??????? ?????? ????? }}: ?????? ??? ??????? |??????= ?? ?????? ????? ??????? |???= ( ?????? ) ????? ?????????: ??????? ?????? ( link )
^ "2-Ethylhexanoic acid" . ACGIH. ????? ?? ????? ?? 2021-11-22 . ???? ???? ?????? 2021-04-09 .
^ "Annex 1 Background Document to the Opinion proposing harmonised classification and labelling at EU level of 2-Ethylhexanoic acid and its salts, with the exception of those specified elsewhere in this Annex" . European Chemicals Agency. 2020. ????? ?? ????? ?? 2021-11-22 . ???? ???? ?????? 2021-04-09 .
^ "Valproic Acid" . The American Society of Health-System Pharmacists. ????? ?? ????? ?? 2017-07-31 . ???? ???? ?????? 2015-10-23 .
^ "Valproate banned without the pregnancy prevention programme" . GOV.UK . ????? ?? ????? ?? 2021-10-27 . ???? ???? ?????? 2018-04-26 .

2-????? ??????? ?? ???????? ??????? :

??? ?????? ????? ?? ?????.

[ROH-1] Helmut Bahrmann? Heinz-Dieter Hahn? Dieter Mayer (2005). "2-Ethylhexanol". Ullmann's Encyclopedia of Industrial Chemistry . Weinheim: Wiley-VCH. DOI : 10.1002/14356007.a10_137 . ISBN : 978-3527306732 .

[2] Fan? Wenlai? Qian? Michael C. (2006). "Characterization of Aroma Compounds of Chinese "Wuliangye" and "Jiannanchun" Liquors by Aroma Extract Dilution Analysis". Journal of Agricultural and Food Chemistry . ?. 54 ?. 7: 2695?2704. DOI : 10.1021/jf052635t . PMID : 16569063 .

[3] Mayuoni-Kirshinbaum? Lina? Tietel? Zipora? Porat? Ron? Ulrich? Detlef (2012). "Identification of aroma-active compounds in 'wonderful' pomegranate fruit using solvent-assisted flavour evaporation and headspace solid-phase micro-extraction methods". European Food Research and Technology . ?. 235 ?. 2: 277?283. DOI : 10.1007/s00217-012-1757-0 . S2CID : 97102092 .

[4] Klaus Rettinger? Christian Burschka? Peter Scheeben? Heike Fuchs? Armin Mosandl (1991). "Chiral 2-alkylbranched acids, esters and alcohols. Preparation and stereospecific flavour evaluation" (PDF) . Tetrahedron: Asymmetry . ?. 2 ?. 10: 965?968. DOI : 10.1016/S0957-4166(00)86137-6 . ????? ?? ????? (PDF) ?? 2021-11-04.

[5] McGinty? D.? Scognamiglio? J.? Letizia? C.S.? Api? A.M. (2010). "Fragrance material review on 2-ethyl-1-hexanol". Food and Chemical Toxicology . ?. 48: S115?S129. DOI : 10.1016/j.fct.2010.05.042 . PMID : 20659633 .

[6] "Rule A-2. Saturated Branched-chain Compounds and Univalent Radicals (ACYCLIC HYDROCARBONS)" . www.acdlabs.com . ????? ?? ????? ?? 2021-08-30.

[7] "Product Spotlight: 2-Ethylhexanol" . 12 ?????? 2019. ????? ?? ????? ?? 2021-04-14.

[aliphald-8] C. Kohlpaintner? M. Schulte? J. Falbe? P. Lappe? J. Weber (2008). "Aldehydes, Aliphatic". Ullmann's Encyclopedia of Industrial Chemistry . Weinheim: Wiley-VCH. DOI : 10.1002/14356007.a01_321.pub2 . ISBN : 978-3527306732 .

[9] Ashford’s Dictionary of Industrial Chemicals, Third edition, 2011, page 4180-4181.

[10] Miller? Robert? Bennett? George (????? 1961). "Producing 2-Ethylhexanol by the Guerbet Reaction". Industrial & Engineering Chemistry . ?. 53 ?. 1: 33?36. DOI : 10.1021/ie50613a027 .

[11] Ernstgard? L.? Norback? D. (2010). "Acute effects of exposure to 1 mg/m(3) of vaporized 2-ethyl-1-hexanol in humans". Indoor Air . ?. 20 ?. 2: 168?75. DOI : 10.1111/j.1600-0668.2009.00638.x . PMID : 20409194 .

[12] Hildenbrand? S.? Wodarz? R. (2009). "Biomonitoring of the di(2-ethylhexyl) phthalate metabolites mono(2-ethyl-5-hydroxyhexyl) phthalate and mono(2-ethyl-5-oxohexyl) phthalate in children and adults during the course of time and seasons". International Journal of Hygiene and Environmental Health . ?. 212 ?. 6: 679?84. DOI : 10.1016/j.ijheh.2009.06.003 . PMID : 19615938 .

[13] Deisinger, PJ, Boatman, RJ, Guest, D (15 Mar 2009). "Metabolism of 2-ethylhexanol administered orally and dermally to the female Fischer-344 rat" . hero.epa.gov (???????????). Archived from the original on 2021-11-22 . Retrieved 2021-04-09 . {{ ??????? ??? }}: ????? ?????????: ????? ??????: ????? ???????? ( link )

[14] Eastman Kodak Company, Eastman Kodak (15 Mar 2009). "Pharmacokinetic studies with 2-ethylhexanol in the female fischer 344 rat (final report) with attachments and cover letter dated 050791" . hero.epa.gov (???????????). Archived from the original on 2021-11-22 . Retrieved 2021-04-09 .

[15] Pennanen? Sirpa? Tuovinen? Kai? Huuskonen? Hannele? Komulainen? Hannu (1992). "The developmental toxicity of 2-ethylhexanoic acid in Wistar rats" . Fundamental and Applied Toxicology . ?. 19 ?. 4: 505?511. DOI : 10.1016/0272-0590(92)90088-Y . PMID : 1426708 . ????? ?? ????? ?? 2021-11-22. {{ ??????? ?????? ????? }}: ?????? ??? ??????? |??????= ?? ?????? ????? ??????? |???= ( ?????? ) ????? ?????????: ??????? ?????? ( link )

[16] "2-Ethylhexanoic acid" . ACGIH. ????? ?? ????? ?? 2021-11-22 . ???? ???? ?????? 2021-04-09 .

[17] "Annex 1 Background Document to the Opinion proposing harmonised classification and labelling at EU level of 2-Ethylhexanoic acid and its salts, with the exception of those specified elsewhere in this Annex" . European Chemicals Agency. 2020. ????? ?? ????? ?? 2021-11-22 . ???? ???? ?????? 2021-04-09 .

[18] "Valproic Acid" . The American Society of Health-System Pharmacists. ????? ?? ????? ?? 2017-07-31 . ???? ???? ?????? 2015-10-23 .

[19] "Valproate banned without the pregnancy prevention programme" . GOV.UK . ????? ?? ????? ?? 2021-10-27 . ???? ???? ?????? 2018-04-26 .

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