?? ?????????? ???????? ?????
?????? ????? ????
(?????? 1952) ?? ????? ????? ????? ???????. ??? ????? ????? ?? ??? ???????? ?????? ?????? ?? ?????? ?????? ?????? ?? ??????? ?????? ???????? .
???????
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???? ???? ??? ???? ??????????? ?? ??? ??????? ?? ????? ????????? ??? 1974. ????? ???? ????????? ?? ???????? ??????? ?? ??? 1977? ????? ???? ????????? ?? ???????? ?????? ??? 1979 ??
??????? ??????????? ?????????
.
[2]
???? ???????? ?????? ????????? ??????
??? ?????? ?????? ??????? ??? A / J ???????? ???????????? ??? ??????? ????????? ?? ??????
[3]
? ??? ???????? ????????? ????? ??
?????? ?? ?????? ?????????? ????? ????? ?????
.
[4]
???? ???? ????? ?? ??? ????????? ?? ?????? ?????? ??????? ??????? ???????? ??????? ?????? ?????? ?????? ??? ??? ??????? ??????? ????????? ???? ???? ??? ??? ????? ?
??????????
? ?????? ???????? ?? ?????? ?????? ?????? ? ??? ???? ??????? ?????? ?? ??????? ?????? ???????.
[5]
?????? ???????
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]
????? ??? 1983 ??? ?????? ?????? ?????? ?? ??????? ?????? ???????? (NIDCR)? ?????? ????? ?????? ?????? ??????? ??????? ?????? ???????? ?? ??? ????? ???? ????? ???????? ???????? ????. ?? ??? 1992 ?????? ???? ????? ???? ???????? ?????? ??????.
?? ??????? 2008-2013 ???? ?????? ?????? ?? ???? ????? ??????? ???????? ??????? NIH (2008-2013) ????? ?????? ???? ?????? ?????? ????? ????? ??????? ??????? ???. ??? ????? ????? ?? ??? ???????? ?????? ?????? ?? ?????? ?????? ?????? ?? ??????? ?????? ???????? (NIDCR).
[5]
?????????? ???????
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]
???? ???? ??? ????? ?????? ?????? ?? ???????? ?????? ????????:
- ????? ??????? ???????? ?????????? ??????? ??????? ????? ????? ??? ??????? (BMSCs)? ??? ?????? ????? ?? ??????? ??????? ???????? ???????? (SSCs) ? ????? ??? ????? ??????? ??????? ???????? ???? ???? ????? ???? ???????? ??????? ?? ??????.
- ????? ??? ????? ????? ???????? ????????? ?? ?????? ??? ????? SSC
- ????? ????? ???? ????? BMSCs / SSCs ?? ????? ?????? ??????
- ????? ?????? ??????? ?????? ?????? ??? ?????? ????? ?????? ?? ???? ?????? ??????. ???????? ??? ??????? BMSCs ?? ????? ???????.
?????? ???????? ???? ????????? ????? ??????? ??????? ??????? ?????? ??????? ??????? ?? ??????? ?????? ????? ??? ??????? ?????? ?????? ??????.
[5]
????? ??????
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